| Product Number |
ARP33088_T100 |
| Product Page |
www.avivasysbio.com/arid4a-antibody-c-terminal-region-arp33088-t100.html |
| Name |
ARID4A Antibody - C-terminal region (ARP33088_T100) |
| Protein Size (# AA) |
1257 amino acids |
| Molecular Weight |
143kDa |
| NCBI Gene Id |
5926 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
AT rich interactive domain 4A (RBP1-like) |
| Alias Symbols |
RBP1, RBBP1, RBP-1, RBBP-1 |
| Peptide Sequence |
Synthetic peptide located within the following region: NSSKCTPVKHLNVSKPQKLARSPARISPHIKDGEKDKHREKHPNSSPRTY |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Meehan,W.J., et al., (2004) J. Biol. Chem. 279 (2), 1562-1569 |
| Description of Target |
ARID4A encodes a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described. |
| Protein Interactions |
SUMO2; SUMO1; HDAC1; BRMS1; HIST2H3C; HIST4H4; UBC; CDK2; CDK1; CCNE1; CCNB1; CCNA2; CCND1; CDK4; SIN3A; SAP30; RB1; SIN3B; RBBP7; RBBP4; ARID4B; HDAC3; EID1; HDAC2; ING2; RBL1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-ARID4A (ARP33088_T100) antibody |
| Blocking Peptide |
For anti-ARID4A (ARP33088_T100) antibody is Catalog # AAP33088 (Previous Catalog # AAPP04121) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human ARID4A |
| Uniprot ID |
P29374 |
| Protein Name |
AT-rich interactive domain-containing protein 4A |
| Publications |
Kondou, H. et al. Sodium-coupled neutral amino acid transporter 4 functions as a regulator of protein synthesis during liver development. Hepatol. Res. (2013). doi:10.1111/hepr.12069 23607685 |
| Protein Accession # |
NP_002883 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_002892 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
ARID4A |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Dog: 100%; Guinea Pig: 79%; Horse: 100%; Human: 100%; Mouse: 92%; Pig: 86%; Rabbit: 86%; Rat: 93% |
| Image 1 | Human HepG2
 | WB Suggested Anti-ARID4A Antibody Titration: 1.25ug/ml
Positive Control: HepG2 cell lysate |
|
