Product Number |
ARP33072_P050 |
Product Page |
www.avivasysbio.com/phkg2-antibody-n-terminal-region-arp33072-p050.html |
Name |
PHKG2 Antibody - N-terminal region (ARP33072_P050) |
Protein Size (# AA) |
406 amino acids |
Molecular Weight |
46kDa |
NCBI Gene Id |
5261 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Phosphorylase kinase, gamma 2 (testis) |
Alias Symbols |
GSD9C |
Peptide Sequence |
Synthetic peptide located within the following region: EDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEV |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Burwinkel,B., et al., (1998) Hum. Mol. Genet. 7 (1), 149-154 |
Description of Target |
Mutations in PHKG2 along with PHKA2 and PHKB, all three different genes of phosphorylase kinase (Phk) subunits, can give rise to glycogen storage disease of the liver. The autosomal-recessive, liver-specific variant of Phk deficiency is caused by mutations in the gene encoding the testis/liver isoform of the catalytic gamma subunit, PHKG2. |
Protein Interactions |
HAUS2; VCP; TP53; CDKN1A; UBC; PRKDC; PHKA2; PHKA1; ATAD3C; DRG1; NDUFA4; TNPO1; FASN; ACACA; GCN1L1; YME1L1; STUB1; SCO2; NPEPPS; VDAC2; ZC3H15; ATAD3A; BZW2; UBE3A; PHKG1; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-PHKG2 (ARP33072_P050) antibody |
Blocking Peptide |
For anti-PHKG2 (ARP33072_P050) antibody is Catalog # AAP33072 (Previous Catalog # AAPP04105) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human PHKG2 |
Uniprot ID |
P15735 |
Protein Name |
Phosphorylase b kinase gamma catalytic chain, testis/liver isoform |
Sample Type Confirmation |
PHKG2 is supported by BioGPS gene expression data to be expressed in HepG2 |
Protein Accession # |
NP_000285 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_000294 |
Tested Species Reactivity |
Human, Mouse |
Gene Symbol |
PHKG2 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Rabbit, Sheep, Zebrafish |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 93% |
Image 1 | Human HepG2
| WB Suggested Anti-PHKG2 Antibody Titration: 0.2-1 ug/ml Positive Control: HepG2 cell lysatePHKG2 is supported by BioGPS gene expression data to be expressed in HepG2 |
|
Image 2 | Mouse Testis, Mouse Small Intestine
| Host: Rabbit Target: PHKG2 Positive control (+): Mouse Testis (M-TE) Negative control (-): Mouse Small Intestine (M-IN) Antibody concentration: 1ug/ml |
|
Image 3 | Mouse Kidney
| Host: Mouse Target Name: PHKG2 Sample Tissue: Mouse Kidney Antibody Dilution: 1ug/ml |
|
Image 4 | Human kidney
| Human kidney |
|