| Product Number |
ARP33068_T100 |
| Product Page |
www.avivasysbio.com/eng-antibody-n-terminal-region-arp33068-t100.html |
| Name |
ENG Antibody - N-terminal region (ARP33068_T100) |
| Protein Size (# AA) |
625 amino acids |
| Molecular Weight |
68kDa |
| NCBI Gene Id |
2022 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Endoglin |
| Alias Symbols |
END, HHT1, ORW1 |
| Peptide Sequence |
Synthetic peptide located within the following region: ILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQ |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Sanz-Rodriguez,F., et al., (2004) J. Biol. Chem. 279 (31), 32858-32868 |
| Description of Target |
Endoglin is a homodimeric transmembrane glycoprotein highly expressed by endothelial cells. It is a component of the transforming growth factor beta receptor complex since it binds TGFB1 and TGFB3 with high affinity. Mutations in the endoglin gene produce hereditary hemorrhagic telangiectasia. |
| Protein Interactions |
ENG; TGFBR2; TGFBR1; TGFB3; TGFB1; ACVRL1; TUFM; TCTEX1D4; TGFBR3; TGFB2; INHBA; BMP7; BMP2; ACVR2A; ACVR1; ACVR2B; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-ENG (ARP33068_T100) antibody |
| Blocking Peptide |
For anti-ENG (ARP33068_T100) antibody is Catalog # AAP33068 (Previous Catalog # AAPP04101) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human ENG |
| Uniprot ID |
P17813 |
| Protein Name |
Endoglin |
| Protein Accession # |
NP_000109 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_000118 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
ENG |
| Predicted Species Reactivity |
Human, Mouse, Rat, Guinea Pig |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Guinea Pig: 91%; Human: 100%; Mouse: 91%; Rat: 91% |
| Image 1 | Human Lung
 | Human Lung |
| | Image 2 | Human Lung Tumor, 293T Cell Lysate
 | Host: Rabbit
Target: ENG
Positive control (+): Human Lung Tumor (T-LU)
Negative control (-): 293T Cell Lysate (2T)
Antibody concentration: 1ug/ml |
| | Image 3 | Human HepG2
 | WB Suggested Anti-ENG Antibody Titration: 2.0ug/ml
Positive Control: HepG2 cell lysate |
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