| Product Number |
ARP33057_T100 |
| Product Page |
www.avivasysbio.com/sox18-antibody-middle-region-arp33057-t100.html |
| Name |
SOX18 Antibody - middle region (ARP33057_T100) |
| Protein Size (# AA) |
384 amino acids |
| Molecular Weight |
41kDa |
| NCBI Gene Id |
54345 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
SRY (sex determining region Y)-box 18 |
| Alias Symbols |
HLTS, HLTRS |
| Peptide Sequence |
Synthetic peptide located within the following region: GSARAFRELPPLGAEFDGLGLPTPERSPLDGLEPGEAAFFPPPAAPEDCA |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Irrthum,A., et al., (2003) Am.J.Hum.Genet.72(6),1470-1478 |
| Description of Target |
SOX18 a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia. |
| Protein Interactions |
GKAP1; MECP2; MEF2C; HMGB1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-SOX18 (ARP33057_T100) antibody |
| Blocking Peptide |
For anti-SOX18 (ARP33057_T100) antibody is Catalog # AAP33057 (Previous Catalog # AAPP04086) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human SOX18 |
| Uniprot ID |
P35713 |
| Protein Name |
Transcription factor SOX-18 |
| Protein Accession # |
NP_060889 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_018419 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
SOX18 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 92%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 85%; Rat: 85% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-SOX18 Antibody Titration: 2.0ug/ml
Positive Control: Jurkat cell lysate |
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