| Product Number |
ARP32842_P050 |
| Product Page |
www.avivasysbio.com/myst2-antibody-n-terminal-region-arp32842-p050.html |
| Name |
MYST2 Antibody - N-terminal region (ARP32842_P050) |
| Protein Size (# AA) |
611 amino acids |
| Molecular Weight |
71kDa |
| NCBI Gene Id |
11143 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
K(lysine) acetyltransferase 7 |
| Alias Symbols |
HBO1, HBOA, MYST2, ZC2HC7 |
| Peptide Sequence |
Synthetic peptide located within the following region: MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLS |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Iizuka,M., (2006) Mol. Cell. Biol. 26 (3), 1098-1108 |
| Description of Target |
MYST2 belongs to the MYST family, which is characterized by a highly conserved C2HC zinc finger and a putative histone acetyltransferase domain. MYST2 specifically represses AR-mediated transcription. MYST2 is a new AR-interacting protein capable of modulating AR activity. It could play a significant role in regulating AR-dependent genes in normal and prostate cancer cells. The biochemical and genetic interactions of MYST family protein MYST2 with two components of the replication apparatus, MCM2 and ORC1, suggest that MYST2-associated HAT activity may play a direct role in the process of DNA replication. MYST2 is a positive regulatory factor for prereplicative complex assembly. |
| Protein Interactions |
UBC; RNF2; EZH2; VIM; CDK11B; APP; HAP1; BARD1; LRIF1; ING4; JADE1; CSNK1E; DYNC1I1; CDT1; tat; HIST1H4A; HIST1H3A; HIST2H2AC; GMNN; ORC2; MCM2; CDC6; JUN; KIAA1377; CEP70; CBX8; CAAP1; KCTD13; PPID; WDR33; NINL; ZBTB8B; HOOK2; KATNBL1; POLB; CALCOCO2; AT |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-KAT7 (ARP32842_P050) antibody |
| Blocking Peptide |
For anti-KAT7 (ARP32842_P050) antibody is Catalog # AAP32842 (Previous Catalog # AAPP03862) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human MYST2 |
| Uniprot ID |
O95251 |
| Protein Name |
Histone acetyltransferase KAT7 |
| Sample Type Confirmation |
KAT7 is supported by BioGPS gene expression data to be expressed in HEK293T |
| Protein Accession # |
NP_008998 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_007067 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
KAT7 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human 293T
 | WB Suggested Anti-MYST2 Antibody Titration: 0.2-1 ug/ml
Positive Control: 293T cell lysateKAT7 is supported by BioGPS gene expression data to be expressed in HEK293T |
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