| Product Number |
ARP32777_P050 |
| Product Page |
www.avivasysbio.com/mxd4-antibody-n-terminal-region-arp32777-p050.html |
| Name |
MXD4 Antibody - N-terminal region (ARP32777_P050) |
| Protein Size (# AA) |
209 amino acids |
| Molecular Weight |
24kDa |
| NCBI Gene Id |
10608 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
MAX dimerization protein 4 |
| Alias Symbols |
MAD4, MST149, MSTP149, bHLHc12 |
| Peptide Sequence |
Synthetic peptide located within the following region: SLLILLEAAEYLERRDREAEHGYASVLPFDGDFAREKTKAAGLVRKAPNN |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Jiang,D.J., et al., (2004) J. Biochem. Mol. Biol. 37 (4), 402-407 |
| Description of Target |
MXD4 is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. |
| Protein Interactions |
TCP10L; UBC; SHBG; SIN3A; MLX; MAX; SMC3; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-MXD4 (ARP32777_P050) antibody |
| Blocking Peptide |
For anti-MXD4 (ARP32777_P050) antibody is Catalog # AAP32777 (Previous Catalog # AAPP03792) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human MXD4 |
| Uniprot ID |
Q14582 |
| Protein Name |
Max dimerization protein 4 |
| Protein Accession # |
NP_006445 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_006454 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
MXD4 |
| Predicted Species Reactivity |
Human, Mouse, Cow, Dog, Guinea Pig, Rabbit, Sheep |
| Application |
WB, IHC |
| Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 93%; Guinea Pig: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Sheep: 93% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-MXD4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysate |
|
| Image 2 | Human Lung Tissue
 | MXD4 antibody - N-terminal region (ARP32777_P050)
Catalog Number: ARP32777_P050
Formalin Fixed Paraffin Embedded Tissue: Human Lung Tissue
Observed Staining: Nucleus of pneumocytes
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1/600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec |
|
