Product Number |
ARP32769_P050 |
Product Page |
www.avivasysbio.com/creb3-antibody-c-terminal-region-arp32769-p050.html |
Name |
CREB3 Antibody - C-terminal region (ARP32769_P050) |
Protein Size (# AA) |
371 amino acids |
Molecular Weight |
41kDa |
NCBI Gene Id |
10488 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
CAMP responsive element binding protein 3 |
Alias Symbols |
LZIP, LUMAN, sLZIP |
Peptide Sequence |
Synthetic peptide located within the following region: YSSDTRGSLPAEHGVLSRQLRALPSEDPYQLELPALQSEVPKDSTHQWLD |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Misra,V., et al., (2005) J. Biol. Chem. 280 (15), 15257-15266 |
Description of Target |
CREB3 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined. |
Protein Interactions |
COPS5; HCFC1; JUN; CREB3L1; CREB3L3; CREB3; NFE2L3; NFE2L2; DDIT3; CEBPG; ATF4; ATF3; TTLL5; RRAS2; OS9; RABAC1; SQLE; BCAT2; CLP1; UBC; HDAC3; MALL; NFIL3; APPBP2; STX8; BNIP2; CCR1; EMD; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-CREB3 (ARP32769_P050) antibody |
Blocking Peptide |
For anti-CREB3 (ARP32769_P050) antibody is Catalog # AAP32769 (Previous Catalog # AAPP03784) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human CREB3 |
Uniprot ID |
Q5TCV1 |
Protein Name |
Cyclic AMP-responsive element-binding protein 3 |
Protein Accession # |
NP_006359 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_006368 |
Tested Species Reactivity |
Human |
Gene Symbol |
CREB3 |
Predicted Species Reactivity |
Human, Rat, Cow, Dog, Horse, Pig, Rabbit |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 92%; Dog: 100%; Horse: 92%; Human: 100%; Pig: 100%; Rabbit: 92%; Rat: 92% |
Image 1 | Human Jurkat
| WB Suggested Anti-CREB3 Antibody Titration: 0.2-1 ug/ml Positive Control: Jurkat cell lysate |
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