HOXC11 Antibody - middle region (ARP32642_T100)

• Product Number: ARP32642_T100
• Name: HOXC11 Antibody - middle region (ARP32642_T100)
• Protein Size (# AA): 304 amino acids
• Molecular Weight: 34kDa
• NCBI Gene Id: 3227
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 1.0 mg/ml
• Gene Full Name: Homeobox C11
• Alias Symbols: HOX3H
• Peptide Sequence: Synthetic peptide located within the following region: DRFFDNAYCGGGDPPAEPPCSGKGEAKGEPEAPPASGLASRAEAGAEAEA
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Kosaki,K., (2002) Teratology 65 (2), 50-62
• Description of Target: HOXC11 belongs to the homeobox family. The homeobox family is a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. HOXC11 is one of several homeobox HOXC proteins. HOXC11 binds to a promoter element of the lactase-phlorizin hydrolase. It may also play a role in early intestinal development.This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined.
• Protein Interactions: HTT; ELAVL1; CD2AP; SOX8; TBX21; GTF2A1L; HDAC5; STAT3; SP1; MEIS1; SMAD3; IRF4; GTF2H1;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-HOXC11 (ARP32642_T100) antibody is Catalog # AAP32642 (Previous Catalog # AAPP03652)
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HOXC11
• Uniprot ID: O43248
• Protein Name: Homeobox protein Hox-C11
• Protein Accession #: NP_055027
• Purification: Protein A purified
• Nucleotide Accession #: NM_014212
• Tested Species Reactivity: Human, Mouse
• Gene Symbol: HOXC11
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
• Application: IHC, WB
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
• Image 1: Transfected 293T
  
  WB Suggested Anti-HOXC11 Antibody Titration: 1.25ug/ml
  Positive Control: Transfected 293T
• Image 2: Mouse lumbar spinal cord
  
  Sample Type:
  Mouse lumbar spinal cord sections
  Primary Antibody Dilution:
  1:1000
  Secondary Antibody:
  Anti-rabbit-Cy3
  Secondary Antibody Dilution:
  1:800
  Color/Signal Descriptions:
  Red: HOXC11
  Gene Name:
  HOXC11
  Submitted by:
  Anonymous
• Image 3: Human RPMI 8226 Whole Cell
  
  Host: Rabbit
  Target Name: HOXC11
  Sample Tissue: Human RPMI 8226 Whole Cell
  Antibody Dilution: 1ug/ml