| Product Number |
ARP32623_P050 |
| Product Page |
www.avivasysbio.com/hic1-antibody-n-terminal-region-arp32623-p050.html |
| Name |
HIC1 Antibody - N-terminal region (ARP32623_P050) |
| Protein Size (# AA) |
733 amino acids |
| Molecular Weight |
77 kDa |
| NCBI Gene Id |
3090 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Hypermethylated in cancer 1 |
| Alias Symbols |
hic-1, ZBTB29, ZNF901 |
| Peptide Sequence |
Synthetic peptide located within the following region: ALCASERRCSPLCGLDLSKKSPPGSAAPERPLAERELPPRPDSPPSAGPA |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Chopin,V. (2006) Med Sci (Paris) 22 (1), 54-61 |
| Description of Target |
HIon Channel1 is a transcriptional repressor. HIon Channel1 may act as a tumor suppressor. HIon Channel1 may be involved in development of head, face, limbs and ventral body wall. Defects in HIon Channel1 may be a cause of the facial dysmorphism and additional birth defects (except for lissencephaly) seen in the contiguous gene disorder Miller-Dieker syndrome (MDS), like defective development of the nose, jaws, extremities, gastrointestinal tract, and kidney. |
| Protein Interactions |
PIAS4; PIAS3; PIAS2; SP1; STAT3; SIRT1; MTA1; UBE2I; SUMO2; HIC2; TCF4; CTBP2; CTBP1; EED; PHF1; EZH2; PHF19; SUZ12; UBC; MBD3; RBBP4; CHD3; SENP3; HDAC4; PIAS1; ARID1A; HIC1; HDAC1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Enhanced Validation |
| Relative Expression (Western Blot) |
 |
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| Datasheets/Manuals |
Printable datasheet for anti-HIC1 (ARP32623_P050) antibody |
| Blocking Peptide |
For anti-HIC1 (ARP32623_P050) antibody is Catalog # AAP32623 (Previous Catalog # AAPP03632) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human HIC1 |
| Uniprot ID |
Q14526-2 |
| Protein Name |
Hypermethylated in cancer 1 protein |
| Protein Accession # |
NP_006488 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_006497 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
HIC1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Guinea Pig |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Guinea Pig: 79%; Human: 100%; Mouse: 79%; Rat: 79% |
| Image 1 |
 | 25 ug of the indicated Human whole cell extracts was loaded onto a 10-20% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment.
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