Product Number |
ARP32565_P050 |
Product Page |
www.avivasysbio.com/taf5l-antibody-middle-region-arp32565-p050.html |
Name |
TAF5L Antibody - middle region (ARP32565_P050) |
Protein Size (# AA) |
589 amino acids |
Molecular Weight |
66kDa |
Subunit |
5L |
NCBI Gene Id |
27097 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
Alias Symbols |
PAF65B |
Peptide Sequence |
Synthetic peptide located within the following region: CVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNG |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Ravnskjaer,K., (2007) EMBO J. 26 (12), 2880-2889 |
Description of Target |
TAF5L functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex.The product of this gene belongs to the WD-repeat TAF5 family of proteins. This gene encodes a protein that is a component of the PCAF histone acetylase complex. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. The encoded protein is structurally similar to one of the histone-like TAFs, TAF5. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. |
Protein Interactions |
HECW2; UBC; KAT2B; LSM11; TADA3; TAF10; ELAVL1; TSC22D1; TTR; H2AFX; CDKN1A; ANXA7; KAT2A; TP53; ATXN7; CEBPE; USP22; ATXN7L3; SUPT3H; TAF9; MYC; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-TAF5L (ARP32565_P050) antibody |
Blocking Peptide |
For anti-TAF5L (ARP32565_P050) antibody is Catalog # AAP32565 (Previous Catalog # AAPP03568) |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human TAF5L |
Uniprot ID |
O75529 |
Protein Name |
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L |
Protein Accession # |
NP_055224 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_014409 |
Tested Species Reactivity |
Human |
Gene Symbol |
TAF5L |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
Image 1 | Human Stomach
| WB Suggested Anti-TAF5L Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Human Stomach |
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