Product Number |
ARP32479_P050 |
Product Page |
www.avivasysbio.com/ncor1-antibody-n-terminal-region-arp32479-p050.html |
Name |
NCOR1 Antibody - N-terminal region (ARP32479_P050) |
Protein Size (# AA) |
2453 amino acids |
Molecular Weight |
270kDa |
NCBI Gene Id |
9611 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Nuclear receptor corepressor 1 |
Alias Symbols |
N-CoR, TRAC1, N-CoR1, hN-CoR, PPP1R109 |
Peptide Sequence |
Synthetic peptide located within the following region: NENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKK |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Horlein,A.J., et al., (1995) Nature 377 (6548), 397-404 |
Description of Target |
NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. |
Protein Interactions |
RARA; TP53; ESR1; PHB2; ZBTB16; THRB; THRA; CREB1; JUN; PPARG; SQSTM1; HDAC3; UBE2I; SOX2; HDAC7; HDAC5; HDAC4; UBC; SKIL; SKI; AR; SMAD4; CSNK2A1; RUNX1T1; CXADR; TBL1XR1; vif; C1D; CHUK; YWHAZ; SMARCE1; SMARCD1; SMARCA2; RBBP4; BPTF; HMGXB4; TAB2; NCOR2 |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-NCOR1 (ARP32479_P050) antibody |
Blocking Peptide |
For anti-NCOR1 (ARP32479_P050) antibody is Catalog # AAP32479 (Previous Catalog # AAPP03478) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human NCOR1 |
Uniprot ID |
Q60974 |
Protein Name |
Nuclear receptor corepressor 1 |
Purification |
Affinity Purified |
Tested Species Reactivity |
Human |
Gene Symbol |
NCOR1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Yeast |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 100%; Rat: 92%; Yeast: 85% |
Image 1 | Human Intestine
| Human Intestine |
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Image 2 | Human Small Intestine
| WB Suggested Anti-NCOR1 Antibody Titration: 0.2-1 ug/ml Positive Control: Human Small Intestine |
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