NCOR1 Antibody - N-terminal region (ARP32479_P050)

Data Sheet
 
Product Number ARP32479_P050
Product Page www.avivasysbio.com/ncor1-antibody-n-terminal-region-arp32479-p050.html
Name NCOR1 Antibody - N-terminal region (ARP32479_P050)
Protein Size (# AA) 2453 amino acids
Molecular Weight 270kDa
NCBI Gene Id 9611
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Nuclear receptor corepressor 1
Alias Symbols N-CoR, TRAC1, N-CoR1, hN-CoR, PPP1R109
Peptide Sequence Synthetic peptide located within the following region: NENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKK
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Horlein,A.J., et al., (1995) Nature 377 (6548), 397-404
Description of Target NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p.
Protein Interactions RARA; TP53; ESR1; PHB2; ZBTB16; THRB; THRA; CREB1; JUN; PPARG; SQSTM1; HDAC3; UBE2I; SOX2; HDAC7; HDAC5; HDAC4; UBC; SKIL; SKI; AR; SMAD4; CSNK2A1; RUNX1T1; CXADR; TBL1XR1; vif; C1D; CHUK; YWHAZ; SMARCE1; SMARCD1; SMARCA2; RBBP4; BPTF; HMGXB4; TAB2; NCOR2
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-NCOR1 (ARP32479_P050) antibody
Blocking Peptide For anti-NCOR1 (ARP32479_P050) antibody is Catalog # AAP32479 (Previous Catalog # AAPP03478)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human NCOR1
Uniprot ID Q60974
Protein Name Nuclear receptor corepressor 1
Purification Affinity Purified
Tested Species Reactivity Human
Gene Symbol NCOR1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Yeast
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 100%; Rat: 92%; Yeast: 85%
Image 1
Human Intestine
Human Intestine
Image 2
Human Small Intestine
WB Suggested Anti-NCOR1 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Small Intestine
 

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