| Product Number |
ARP32447_P050 |
| Product Page |
www.avivasysbio.com/pcbd1-antibody-n-terminal-region-arp32447-p050.html |
| Name |
PCBD1 Antibody - N-terminal region (ARP32447_P050) |
| Protein Size (# AA) |
104 amino acids |
| Molecular Weight |
12kDa |
| NCBI Gene Id |
5092 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha |
| Alias Symbols |
PCD, PHS, DCOH, PCBD |
| Peptide Sequence |
Synthetic peptide located within the following region: MAGKAHRLSAEERDQLLPNLRAVGWNELEGRDAIFKQFHFKDFNRAFGFM |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Hevel,J.M., (2006) Mol. Genet. Metab. 88 (1), 38-46 |
| Description of Target |
PCBD1 is pterin-4 alpha-carbinolamine dehydratase, an enzyme involved in phenylalanine hydroxylation. A deficiency of this enzyme leads to hyperphenylalaninemia. The enzyme regulates the homodimerization of the transcription factor hepatocyte nuclear factor 1 (HNF1).This gene encodes pterin-4 alpha-carbinolamine dehydratase, an enzyme involved in phenylalanine hydroxylation. A deficiency of this enzyme leads to hyperphenylalaninemia. The enzyme regulates the homodimerization of the transcription factor hepatocyte nuclear factor 1 (HNF1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Protein Interactions |
TFF3; PCBD1; LNX1; FXR2; ACIN1; RPS24; APP; CDK5RAP2; UBC; HNF1A; DCUN1D1; COPS5; CUL1; CUL3; CUL4A; CUL4B; CUL5; MYC; ZNF567; ZNF714; TRIM5; PCBD2; EHMT1; SOWAHC; PAPOLG; HES4; CALCOCO1; MIS18BP1; KLF13; BRD7; ZNF451; DIP2C; SCMH1; POLR3A; WWP1; DENND4A; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-PCBD1 (ARP32447_P050) antibody |
| Blocking Peptide |
For anti-PCBD1 (ARP32447_P050) antibody is Catalog # AAP32447 (Previous Catalog # AAPP03443) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human PCBD1 |
| Uniprot ID |
P61457 |
| Protein Name |
Pterin-4-alpha-carbinolamine dehydratase |
| Protein Accession # |
NP_000272 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_000281 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
PCBD1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human Liver
 | WB Suggested Anti-PCBD1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human Liver |
|
