| Product Number |
ARP32446_T100 |
| Product Page |
www.avivasysbio.com/pax3-antibody-middle-region-arp32446-t100.html |
| Name |
PAX3 Antibody - middle region (ARP32446_T100) |
| Protein Size (# AA) |
403 amino acids |
| Molecular Weight |
45kDa |
| NCBI Gene Id |
5077 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Paired box 3 |
| Alias Symbols |
WS1, WS3, CDHS, HUP2 |
| Peptide Sequence |
Synthetic peptide located within the following region: KGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Wachtel,M., et al., (2004) Cancer Res. 64 (16), 5539-5545 |
| Description of Target |
PAX3 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. |
| Protein Interactions |
PCTP; UBC; TAF1; POU3F2; HDAC1; TRIM28; HDAC10; SOX8; WWTR1; PAX3; DAXX; CIB1; SOX10; MEOX2; MEOX1; MITF; MSX1; Rad23b; PSMD4; TBP; IPO13; CNR1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-PAX3 (ARP32446_T100) antibody |
| Blocking Peptide |
For anti-PAX3 (ARP32446_T100) antibody is Catalog # AAP32446 (Previous Catalog # AAPP03442) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human PAX3 |
| Uniprot ID |
Q86UQ3 |
| Protein Name |
Paired box protein Pax-3 |
| Protein Accession # |
NP_852126 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_181461 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
PAX3 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human Liver
 | WB Suggested Anti-PAX3 Antibody Titration: 2.5ug/ml
Positive Control: Human Liver |
|
|
