LEF1 Antibody - middle region (ARP32404_P050)

Data Sheet
 
Product Number ARP32404_P050
Product Page www.avivasysbio.com/lef1-antibody-middle-region-arp32404-p050.html
Name LEF1 Antibody - middle region (ARP32404_P050)
Protein Size (# AA) 399 amino acids
Molecular Weight 44kDa
NCBI Gene Id 51176
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Lymphoid enhancer-binding factor 1
Alias Symbols LEF-1, TCF10, TCF7L3, TCF1ALPHA
Peptide Sequence Synthetic peptide located within the following region: ADIKSSLVNESEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGG
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Description of Target Lymphoid enhancer-binding factor-1 (LEF1) is a 48-kD nuclear protein that is expressed in pre-B and T cells. It binds to a functionally important site in the T-cell receptor-alpha (TCRA) enhancer and confers maximal enhancer activity. LEF1 belongs to a family of regulatory proteins that share homology with high mobility group protein-1 (HMG1).
Protein Interactions RNF138; UBC; RNF14; NLK; NARF; STAT5A; PITX2; CTNNB1; CDX1; DPYSL2; nrarp; FHIT; MITF; HINT1; TLE2; TLE1; SETD8; MYB; E2F1; HDAC1; ZBTB3; DACT1; DAZAP2; ALYREF; PIAS4; ALX4; SMAD3; SUMO2; EP300; SMAD1; SMAD2; SMAD4; KPNA1; KPNA2; UBTF; RUNX2; NOTCH1; RUVB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-LEF1 (ARP32404_P050) antibody
Blocking Peptide For anti-LEF1 (ARP32404_P050) antibody is Catalog # AAP32404 (Previous Catalog # AAPP03395)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human LEF1
Uniprot ID Q9UJU2
Protein Name Lymphoid enhancer-binding factor 1
Protein Accession # NP_057353
Purification Affinity Purified
Nucleotide Accession # NM_016269
Tested Species Reactivity Human
Gene Symbol LEF1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Pig, Rabbit
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 86%; Human: 100%; Mouse: 79%; Pig: 93%; Rabbit: 93%; Rat: 79%
Image 1
Human HepG2
WB Suggested Anti-LEF1 Antibody Titration: 0.1-2.0ug/ml
Positive Control: HepG2 cell lysate
Image 2
Human Fetal Heart
Host: Rabbit
Target Name: LEF1
Sample Type: Human Fetal Heart
Antibody Dilution: 1.0ug/ml
 

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