| Product Number |
ARP32379_P050 |
| Product Page |
www.avivasysbio.com/ruvbl2-antibody-n-terminal-region-arp32379-p050.html |
| Name |
RUVBL2 Antibody - N-terminal region (ARP32379_P050) |
| Protein Size (# AA) |
463 amino acids |
| Molecular Weight |
51kDa |
| NCBI Gene Id |
10856 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
RuvB-like 2 (E. coli) |
| Alias Symbols |
RVB2, TIH2, ECP51, TIP48, CGI-46, ECP-51, INO80J, REPTIN, TIP49B, TAP54-beta |
| Peptide Sequence |
Synthetic peptide located within the following region: IDRPATGTGSKVGKLTLKTTEMETIYDLGTKMIESLTKDKVQAGDVITID |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Bauer,A., et al., (2000) EMBO J. 19 (22), 6121-6130 |
| Description of Target |
RUVBL2 encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. |
| Protein Interactions |
CCDC103; LNX1; RUVBL1; UBC; DPCD; HUWE1; VCP; SUMO2; RPAP3; MDM2; RPA3; RPA2; RPA1; SUZ12; EED; RNF2; BMI1; CDKN2A; ASNA1; PPP6R3; PLA2G4A; PARK2; FBXO6; TARDBP; YWHAQ; PPP6R2; EXOSC10; BAG3; POLR2E; UPF1; SMG1; RBM8A; TTI1; PAN2; TBP; CTNNB1; STOM; RUVBL |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-RUVBL2 (ARP32379_P050) antibody |
| Blocking Peptide |
For anti-RUVBL2 (ARP32379_P050) antibody is Catalog # AAP32379 (Previous Catalog # AAPP03369) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human RUVBL2 |
| Uniprot ID |
Q9Y230 |
| Protein Name |
RuvB-like 2 |
| Publications |
Barthéléry, M., Jaishankar, A., Salli, U. & Vrana, K. E. Reptin52 expression during in vitro neural differentiation of human embryonic stem cells. Neurosci. Lett. 452, 47-51 (2009). 19444951 |
| Sample Type Confirmation |
RUVBL2 is supported by BioGPS gene expression data to be expressed in K562 |
| Protein Accession # |
NP_006657 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_006666 |
| Tested Species Reactivity |
Human, Mouse |
| Gene Symbol |
RUVBL2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93% |
| Image 1 | Human HepG2
 | WB Suggested Anti-RUVBL2 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate |
|
| Image 2 | Human Testis
 | Rabbit Anti-RUVBL2 antibody
Catalog Number: ARP32379
Formalin Fixed Paraffin Embedded Tissue: Human Testis
Primary antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20x
Exposure Time: 0.5-2.0sec
|
|
| Image 3 | Human Liver
 | Human Liver |
|
| Image 4 | K562
 | WB Suggested Anti-RUVBL2 Antibody
Positive Control: Lane 1: 30ug K562 lysate
Primary Antibody Dilution : 1:200
Secondary Antibody : Anti-rabbit-HRP
Secondry Antibody Dilution : 1:1000
Submitted by: Sustackova GabrielaRUVBL2 is supported by BioGPS gene expression data to be expressed in K562 |
|
| Image 5 | Mouse Kidney
 | Host: Mouse
Target Name: RUVBL2
Sample Tissue: Mouse Kidney
Antibody Dilution: 1ug/ml |
|
