TLE3 Antibody - N-terminal region (ARP32362_T100)

Data Sheet
 
Product Number ARP32362_T100
Product Page www.avivasysbio.com/tle3-antibody-n-terminal-region-arp32362-t100.html
Name TLE3 Antibody - N-terminal region (ARP32362_T100)
Protein Size (# AA) 772 amino acids
Molecular Weight 83kDa
NCBI Gene Id 7090
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
Alias Symbols ESG, ESG3, GRG3, HsT18976
Peptide Sequence Synthetic peptide located within the following region: GSSSGLLALGALGSQAHLTVKDEKNHHELDHRERESSANNSVSPSESLRA
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Liu,Y., et al., (1996) Genomics 31 (1), 58-64
Description of Target The TLE genes are differentially expressed and encode nuclear proteins, consistent with the presence of sequence motifs associated with nuclear functions. These genes are the human homologues of Drosophila groucho, a member of the Notch signaling pathway which controls a number of different cell-fate choices in invertebrates and vertebrates.
Protein Interactions UBC; COPG1; COPZ1; TBC1D4; PIN1; KLC1; COPB1; ARCN1; NLK; UBD; SRXN1; SEC24A; AHCYL1; SSSCA1; ALYREF; UBA2; S100A9; PPM1G; IGBP1; APP; HINFP; tcf7l1a; lnx2b; NDRG1; CUL4B; SIX3; FOXG1; AES; SIX4;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-TLE3 (ARP32362_T100) antibody
Blocking Peptide For anti-TLE3 (ARP32362_T100) antibody is Catalog # AAP32362 (Previous Catalog # AAPP03351)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human TLE3
Uniprot ID Q04726
Protein Name Transducin-like enhancer protein 3
Protein Accession # NP_005069
Purification Protein A purified
Nucleotide Accession # NM_005078
Tested Species Reactivity Human
Gene Symbol TLE3
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 93%; Rat: 93%; Zebrafish: 79%
Image 1
Human HepG2
WB Suggested Anti-TLE3 Antibody Titration: 2.5ug/ml
Positive Control: HepG2 cell lysate
 

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