Product Number |
ARP32335_T100 |
Product Page |
www.avivasysbio.com/id3-antibody-n-terminal-region-arp32335-t100.html |
Name |
ID3 Antibody - N-terminal region (ARP32335_T100) |
Protein Size (# AA) |
119 amino acids |
Molecular Weight |
13kDa |
NCBI Gene Id |
3399 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
Description |
|
Alias Symbols |
HEIR-1, bHLHb25 |
Peptide Sequence |
Synthetic peptide located within the following region: MKALSPVRGCYEAVCCLSERSLAIARGRGKGPAAEEPLSLLDDMNHCYSR |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Tsuchiya,T., (2005) Cancer Sci. 96 (11), 784-790 |
Description of Target |
ID3 is a member of the ID family. The members of the family of helix-loop-helix (HLH) proteins lack a basic DNA-binding domain and inhibit transcription through formation of nonfunctional dimers that are incapable of binding to DNA.Members of the ID family of helix-loop-helix (HLH) proteins lack a basic DNA-binding domain and inhibit transcription through formation of nonfunctional dimers that are incapable of binding to DNA.[supplied by OMIM]. |
Protein Interactions |
UBC; TCF12; TCF3; TCF4; FAM74A1; ZNF626; ZNF408; RND1; PUF60; ZNF3; MLX; CNOT3; ID3; GNB2; FHL2; CSK; ATF3; CDK2; SMURF2; PRDM14; CBFA2T2; SAP30; IKBKG; E2F4; GATA4; NKX2-5; ID4; GTF2A1L; ELK4; ELK1; SREBF1; PAX5; MYF6; MYF5; MYOG; MYOD1; IFI16; HES1; RUN |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-ID3 (ARP32335_T100) antibody |
Blocking Peptide |
For anti-ID3 (ARP32335_T100) antibody is Catalog # AAP32335 (Previous Catalog # AAPP03322) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human ID3 |
Uniprot ID |
Q02535 |
Protein Name |
DNA-binding protein inhibitor ID-3 |
Publications |
Inhibitor of differentiation 4 (Id4) is a potential tumor suppressor in prostate cancer. BMC Cancer. 9, 173 (2009). 19500415 |
Protein Accession # |
NP_002158 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_002167 |
Tested Species Reactivity |
Human |
Gene Symbol |
ID3 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 79%; Pig: 100%; Rabbit: 100%; Rat: 93%; Sheep: 93% |
Image 1 | Transfected 293T
| WB Suggested Anti-ID3 Antibody Titration: 1.25ug/ml Positive Control: Transfected 293T |
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