| Product Number |
ARP32300_T100 |
| Product Page |
www.avivasysbio.com/foxc1-antibody-c-terminal-region-arp32300-t100.html |
| Name |
FOXC1 Antibody - C-terminal region (ARP32300_T100) |
| Protein Size (# AA) |
553 amino acids |
| Molecular Weight |
57kDa |
| NCBI Gene Id |
2296 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Forkhead box C1 |
| Description |
|
| Alias Symbols |
ARA, IGDA, IHG1, ASGD3, FKHL7, IRID1, RIEG3, FREAC3, FREAC-3 |
| Peptide Sequence |
Synthetic peptide located within the following region: GERGGHLQGAPGGAGGSAVDNPLPDYSLPPVTSSSSSSLSHGGGGGGGGG |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Mortemousque,B., et al., (2004) Arch. Ophthalmol. 122 (10), 1527-1533 |
| Description of Target |
FOXC1 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly. |
| Protein Interactions |
SOX2; gag-pol; ELAVL1; SUMO2; UBC; HMGB1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-FOXC1 (ARP32300_T100) antibody |
| Blocking Peptide |
For anti-FOXC1 (ARP32300_T100) antibody is Catalog # AAP32300 (Previous Catalog # AAPP03282) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human FOXC1 |
| Uniprot ID |
Q12948 |
| Protein Name |
Forkhead box protein C1 |
| Publications |
Potential for transcriptional upregulation of cochlin in glaucomatous trabecular meshwork: a combinatorial bioinformatic and biochemical analytical approach. Invest Ophthalmol Vis Sci. 50, 3106-11 (2009). 19098315 |
| Protein Accession # |
NP_001444 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_001453 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
FOXC1 |
| Predicted Species Reactivity |
Human, Mouse, Rat |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Human: 93%; Mouse: 86%; Rat: 86% |
| Image 1 | Human HepG2
 | WB Suggested Anti-FOXC1 Antibody Titration: 5.0ug/ml
Positive Control: HepG2 cell lysate |
|
