Product Number |
ARP32294_P050 |
Product Page |
www.avivasysbio.com/skiip-antibody-n-terminal-region-arp32294-p050.html |
Name |
SKIIP Antibody - N-terminal region (ARP32294_P050) |
Protein Size (# AA) |
536 amino acids |
Molecular Weight |
61kDa |
NCBI Gene Id |
22938 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
SNW domain containing 1 |
Alias Symbols |
Bx42, SKIP, FUN20, Prp45, SKIIP, SKIP1, PRPF45, NCOA-62 |
Peptide Sequence |
Synthetic peptide located within the following region: RQGQSKDKVIYSKYTDLVPKEVMNADDPDLQRPDEEAIKEITEKTRVALE |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Figueroa,J.D., et al., (2004) Eur.Res.Commun.319(4),1105-1109 |
Description of Target |
SKIIP (Nuclear Protein SkiP, nuclear receptor coactivator NCoA-62, ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. |
Protein Interactions |
TRAF1; GOLGA2; KRT40; LZTS2; RINT1; TEX11; CEP55; PPIL1; TFIP11; MTUS2; IKZF1; TP53; TUBGCP3; AURKB; UBC; SUZ12; RNF2; BMI1; HECW2; HDAC11; Dlg4; TTC14; ZNF830; SNIP1; CXorf56; XAB2; CTNNBL1; SART1; NHP2L1; MFAP1; EIF4A3; MAGOH; DHX15; DDX5; PABPC1; SKIV2 |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-SNW1 (ARP32294_P050) antibody |
Blocking Peptide |
For anti-SNW1 (ARP32294_P050) antibody is Catalog # AAP32294 (Previous Catalog # AAPP03276) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human SKIIP |
Uniprot ID |
Q13573 |
Protein Name |
SNW domain-containing protein 1 |
Sample Type Confirmation |
SNW1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat |
Protein Accession # |
NP_036377 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_012245 |
Tested Species Reactivity |
Human |
Gene Symbol |
SNW1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Yeast |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 83% |
Image 1 | Human Jurkat
| WB Suggested Anti-SKIIP Antibody Titration: 0.2-1 ug/ml Positive Control: Jurkat cell lysateSNW1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells |
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Image 2 | Human Lung
| Rabbit Anti-SKIIP antibody Catalog Number: ARP32294_P050 Paraffin Embedded Tissue: Human Lung cell Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
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Image 3 | Human Intestine
| Human Intestine |
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