| Product Number |
ARP32264_P050 |
| Product Page |
www.avivasysbio.com/etv5-antibody-n-terminal-region-arp32264-p050.html |
| Name |
ETV5 Antibody - N-terminal region (ARP32264_P050) |
| Protein Size (# AA) |
510 amino acids |
| Molecular Weight |
58kDa |
| NCBI Gene Id |
2119 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Ets variant 5 |
| Alias Symbols |
ERM |
| Peptide Sequence |
Synthetic peptide located within the following region: AQVPDDEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSELSSCSHEQALGA |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Degerny,C., (2005) J. Biol. Chem. 280 (26), 24330-24338 |
| Description of Target |
ETV5 Contains 1 ETS DNA-binding domain and belongs to the ETS family. The ETV5 gene expression is regulated by the conventional PKC (cPKC) pathway.ETV5 is subject to SUMO modification and this post-translational modification causes inhibition of transcription-enhancing activity Phosphorylated ETV5 and the actin cytoskeleton regulate CD44-mediated hyaluronan binding in myeloid cells. ERMs (ezrin/radixin/moesin) function as adaptor molecules in the interactions of adhesion receptors and intracellular tyrosine kinases. ETV5 can cooperate with c-Jun and has a role in progression of breast cancer |
| Protein Interactions |
RFWD2; HDAC11; DHRS7; SEZ6L2; SLC22A2; HOXD9; CYP3A5; CCR5; CISH; AMH; APP; BRCA1; ELAVL1; SUMO2; UBC; AR; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-ETV5 (ARP32264_P050) antibody |
| Blocking Peptide |
For anti-ETV5 (ARP32264_P050) antibody is Catalog # AAP32264 (Previous Catalog # AAPP03245) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human ETV5 |
| Uniprot ID |
P41161 |
| Protein Name |
ETS translocation variant 5 |
| Protein Accession # |
NP_004445 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_004454 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
ETV5 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86% |
| Image 1 | Human 293T
 | WB Suggested Anti-ETV5 Antibody Titration: 0.2-1 ug/ml
Positive Control: 293T cell lysate |
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