| Product Number |
ARP32151_P050 |
| Product Page |
www.avivasysbio.com/rnf12-antibody-c-terminal-region-arp32151-p050.html |
| Name |
RNF12 Antibody - C-terminal region (ARP32151_P050) |
| Protein Size (# AA) |
624 amino acids |
| Molecular Weight |
69kDa |
| NCBI Gene Id |
51132 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Ring finger protein, LIM domain interacting |
| Alias Symbols |
MRX61, RNF12, TOKAS, NY-REN-43 |
| Peptide Sequence |
Synthetic peptide located within the following region: AQFFLLNEDDDDQPRGLTKEQIDNLAMRSFGENDALKTCSVCITEYTEGN |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Hiratani, I.,et al., (2003) Development 130 (17), 4161-4175 |
| Description of Target |
RNF12 is a RING-H2 zinc finger protein. It has been shown to be a ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Alternatively spliced transcript variants encoding the same protein have been reported. |
| Protein Interactions |
STMN1; SNX17; UBC; RPS14; TNFAIP3; UBE2D1; LNX2; TERF1; SMURF2; HHV8GK18_gp81; HDAC2; REXO1; TOLLIP; LDB1; UBXN1; UBE2E2; SIAH1; SS18L1; STAT6; UBE2D4; UBE2E1; UBE2D3; UBE2D2; LDB2; SIN3A; PDLIM1; LHX1; LHX2; LIMK1; LHX3; ISL1; LMO2; RLIM; ESR1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-RLIM (ARP32151_P050) antibody |
| Blocking Peptide |
For anti-RLIM (ARP32151_P050) antibody is Catalog # AAP32151 (Previous Catalog # AAPP03121) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human RNF12 |
| Uniprot ID |
Q9NVW2 |
| Protein Name |
E3 ubiquitin-protein ligase RLIM |
| Sample Type Confirmation |
RLIM is supported by BioGPS gene expression data to be expressed in Jurkat |
| Protein Accession # |
NP_057204 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_016120 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
RLIM |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Yeast, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93%; Yeast: 89%; Zebrafish: 93% |
| Image 1 | Human Spermatophore
 | Human Spermatophore |
|
| Image 2 | Human Jurkat
 | WB Suggested Anti-RNF12 Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysateRLIM is supported by BioGPS gene expression data to be expressed in Jurkat |
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