PBX2 Antibody - N-terminal region (ARP32069_P050)

• Product Number: ARP32069_P050
• Name: PBX2 Antibody - N-terminal region (ARP32069_P050)
• Protein Size (# AA): 430 amino acids
• Molecular Weight: 46kDa
• NCBI Gene Id: 5089
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: Pre-B-cell leukemia homeobox 2
• Alias Symbols: G17, HOX12, PBX2MHC
• Peptide Sequence: Synthetic peptide located within the following region: MDERLLGPPPPGGGRGGLGLVSGEPGGPGEPPGGGDPGGGSGGVPGGRGK
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Lehner,B., (2004) Genomics 83 (1), 153-167
• Description of Target: PBX2 is a ubiquitously expressed member of the TALE/PBX homeobox family. PBX2 gene was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. PBX2 is a transcriptional activator which binds to the TLX1 promoter. This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.
• Protein Interactions: CARD9; HOXA1; SOX2; ELAVL1; COPS6; ZDHHC7; SKIV2L2; SMYD3; MCRS1; CCDC88B; RPS6KC1; PBX2; PBX1; CENPBD1; DCTN3; NUP62; BAIAP2; IKBKAP; UBE2E1; PKNOX1; BLOC1S1; RPL4; HOXB8; HOXA9;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-PBX2 (ARP32069_P050) antibody is Catalog # AAP32069 (Previous Catalog # AAPP02971)
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PBX2
• Uniprot ID: P40425
• Protein Name: Pre-B-cell leukemia transcription factor 2
• Protein Accession #: NP_002577
• Purification: Affinity Purified
• Nucleotide Accession #: NM_002586
• Tested Species Reactivity: Mouse
• Gene Symbol: PBX2
• Predicted Species Reactivity: Human, Mouse, Rat, Guinea Pig, Horse
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%
• Image 1: Transfected 293T
  
  WB Suggested Anti-PBX2 Antibody Titration: 0.2-1 ug/ml
  Positive Control: Transfected 293T
• Image 2: Mouse Pancreas
  
  Host: Mouse
  Target Name: PBX2
  Sample Tissue: Mouse Pancreas
  Antibody Dilution: 1ug/ml