MYCN Antibody - C-terminal region (ARP32030_T100)

Data Sheet
 
Product Number ARP32030_T100
Product Page www.avivasysbio.com/mycn-antibody-c-terminal-region-arp32030-t100.html
Name MYCN Antibody - C-terminal region (ARP32030_T100)
Protein Size (# AA) 464 amino acids
Molecular Weight 50kDa
NCBI Gene Id 4613
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name V-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
Alias Symbols NMYC, ODED, MODED, N-myc, bHLHe37
Peptide Sequence Synthetic peptide located within the following region: EDAPPQKKIKSEASPRPLKSVIPPKAKSLSPRNSDSEDSERRRNHNILER
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Hansford,L.M., et al., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (34), 12664-12669
Description of Target MYCN is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. It is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas
Protein Interactions TRIM32; UBC; HDAC5; NMI; MAX; CDKN2A; GRK5; ZBTB17; SIRT1; YEATS4; CSNK1E; FBXW7; PIAS2; AURKA; SP1; NTRK1; NGFR; HDAC2; CSNK2A1; YAF2; MXD1; CSNK2A2; SLC1A2;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-MYCN (ARP32030_T100) antibody
Blocking Peptide For anti-MYCN (ARP32030_T100) antibody is Catalog # AAP32030 (Previous Catalog # AAPP02932)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human MYCN
Uniprot ID P04198
Protein Name N-myc proto-oncogene protein
Protein Accession # NP_005369
Purification Protein A purified
Nucleotide Accession # NM_005378
Tested Species Reactivity Human
Gene Symbol MYCN
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 92%; Rabbit: 77%; Rat: 92%
Image 1
Human Heart
WB Suggested Anti-MYCN Antibody Titration: 2.5ug/ml
Positive Control: Human heart
 

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