Product Number |
ARP32030_T100 |
Product Page |
www.avivasysbio.com/mycn-antibody-c-terminal-region-arp32030-t100.html |
Name |
MYCN Antibody - C-terminal region (ARP32030_T100) |
Protein Size (# AA) |
464 amino acids |
Molecular Weight |
50kDa |
NCBI Gene Id |
4613 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
V-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) |
Alias Symbols |
NMYC, ODED, MODED, N-myc, bHLHe37 |
Peptide Sequence |
Synthetic peptide located within the following region: EDAPPQKKIKSEASPRPLKSVIPPKAKSLSPRNSDSEDSERRRNHNILER |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Hansford,L.M., et al., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (34), 12664-12669 |
Description of Target |
MYCN is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. It is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas |
Protein Interactions |
TRIM32; UBC; HDAC5; NMI; MAX; CDKN2A; GRK5; ZBTB17; SIRT1; YEATS4; CSNK1E; FBXW7; PIAS2; AURKA; SP1; NTRK1; NGFR; HDAC2; CSNK2A1; YAF2; MXD1; CSNK2A2; SLC1A2; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-MYCN (ARP32030_T100) antibody |
Blocking Peptide |
For anti-MYCN (ARP32030_T100) antibody is Catalog # AAP32030 (Previous Catalog # AAPP02932) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human MYCN |
Uniprot ID |
P04198 |
Protein Name |
N-myc proto-oncogene protein |
Protein Accession # |
NP_005369 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_005378 |
Tested Species Reactivity |
Human |
Gene Symbol |
MYCN |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 92%; Rabbit: 77%; Rat: 92% |
Image 1 | Human Heart
| WB Suggested Anti-MYCN Antibody Titration: 2.5ug/ml Positive Control: Human heart |
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