SMAD7 Antibody - N-terminal region (ARP32008_P050)

Data Sheet
 
Product Number ARP32008_P050
Product Page www.avivasysbio.com/smad7-antibody-n-terminal-region-arp32008-p050.html
Name SMAD7 Antibody - N-terminal region (ARP32008_P050)
Protein Size (# AA) 426 amino acids
Molecular Weight 46kDa
NCBI Gene Id 4092
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name SMAD family member 7
Description
Alias Symbols CRCS3, MADH7, MADH8
Peptide Sequence Synthetic peptide located within the following region: EEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHH
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Komuro,A., et al., (2004) Oncogene 23 (41), 6914-6923
Description of Target Smad7 acts to functionally inactivate RB and de-repress E2F without blocking the activation of TbetaRI and the nuclear translocation of Smad2/3, allowing TGF-beta1 to exert effects in a cancer cell that is resistant to TGF-beta1-mediated growth inhibition.
Protein Interactions HDAC3; HDAC2; USP11; SMURF2; SMURF1; SKP2; MYC; Melk; HCVgp1; RNF111; KDM2A; SOX13; PIAS1; SOX7; UBE2O; MKL2; ASH1L; PIAS4; CXXC5; ZNF107; ZBTB11; HEYL; TTF2; UBC; TTF1; SOX5; MYOD1; XRCC6; CTNNB1; MAPK14; BAMBI; PPP1R15A; NEDD4L; STAMBP; YAP1; AXIN1; TP5
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-SMAD7 (ARP32008_P050) antibody
Blocking Peptide For anti-SMAD7 (ARP32008_P050) antibody is Catalog # AAP32008
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human SMAD7
Uniprot ID O15105
Protein Name Mothers against decapentaplegic homolog 7
Publications

Higher Anti-Liver Fibrosis Effect of Cordyceps militaris-Fermented Product Cultured with Deep Ocean Water via Inhibiting Proinflammatory Factors and Fibrosis-Related Factors Expressions. Mar Drugs. 15, (2017). 28594374

Protein Accession # NP_005895
Purification Affinity Purified
Nucleotide Accession # NM_005904
Tested Species Reactivity Human
Gene Symbol SMAD7
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Pig, Rabbit
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 93%; Dog: 93%; Human: 100%; Mouse: 92%; Pig: 93%; Rabbit: 93%; Rat: 85%
Image 1
Human Lung
Host: Rabbit
Target Name: SMAD7
Sample Type: Human Lung
Antibody Dilution: 1.0 ug/ml
Image 2
Transfected 293 extracts
WB Suggested Anti-SMAD7 Antibody
Positive Control: Lane 1: 2ug Flag-SMAD7 transfected 293 extracts
Primary Antibody Dilution : 1:500
Secondary Antibody : Goat anti-rabbit-HRP
Secondry Antibody Dilution : 1:5000
Submitted by: Anonymous
 

AVIVA SYSTEMS BIOLOGY manufactures and sells quality antibody products covering genome wide proteins.

AVIVA SYSTEMS BIOLOGY
10211 Pacific Mesa Blvd, Ste 401, San Diego, CA 92121 USA | Tel: (858)552-6979 | info@avivasysbio.com