HOXA13 Antibody - middle region (ARP31955_P050)

• Product Number: ARP31955_P050
• Name: HOXA13 Antibody - middle region (ARP31955_P050)
• Protein Size (# AA): 388 amino acids
• Molecular Weight: 40kDa
• NCBI Gene Id: 3209
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: Homeobox A13
• Alias Symbols: HOX1, HOX1J
• Peptide Sequence: Synthetic peptide located within the following region: AAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAA
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Description of Target: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome.
• Protein Interactions: UBC; MEIS3; SMAD5; MEIS2; MEIS1; SMAD1; SMAD2;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-HOXA13 (ARP31955_P050) antibody is Catalog # AAPY04304
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HOXA13
• Uniprot ID: P31271
• Protein Name: Homeobox protein Hox-A13
• Publications:

  Villavicencio-Lorini, P. et al. Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation. J. Clin. Invest. 120, 1994-2004 (2010). 20458143

• Protein Accession #: NP_000513
• Purification: Affinity Purified
• Nucleotide Accession #: NM_000522
• Tested Species Reactivity: Human
• Gene Symbol: HOXA13
• Predicted Species Reactivity: Human, Mouse, Dog
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Dog: 83%; Human: 100%; Mouse: 92%
• Image 1: Human Jurkat
  
  WB Suggested Anti-HOXA13 Antibody Titration: 0.2-1 ug/ml
  ELISA Titer: 1:62500
  Positive Control: Jurkat cell lysate