GTF2I Antibody - N-terminal region (ARP31910_P050)

• Product Number: ARP31910_P050
• Name: GTF2I Antibody - N-terminal region (ARP31910_P050)
• Protein Size (# AA): 978 amino acids
• Molecular Weight: 110kDa
• NCBI Gene Id: 2969
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: General transcription factor IIi
• Alias Symbols: WBS, DIWS, SPIN, IB291, BAP135, BTKAP1, TFII-I, WBSCR6, GTFII-I
• Peptide Sequence: Synthetic peptide located within the following region: ILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQGSH
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Morris,C.A., et al., (2003) Am. J. Med. Genet. 123A (1), 45-59
• Description of Target: GTF2I encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. The exon(s) encoding 5' UTR has not been fully defined, but this gene is known to contain at least 34 exons, and its alternative splicing generates 4 transcript variants.
• Protein Interactions: TP53; ZMYM3; PIAS2; TUBG1; TRAF6; SUMO2; SUMO3; AP2B1; DPY30; GCC1; MTUS2; MDM2; UBC; SUMO1; RPA3; RPA2; RPA1; EED; RNF2; SUZ12; CTPS2; WARS; RPL28; RAD23B; PRPS2; PRKDC; NUCB1; METTL1; ADSL; FBXO6; UBD; CBX2; TAB2; AP4S1; CBX4; MAPK12; C4BPA; MAP3K3; SLU
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-GTF2I (ARP31910_P050) antibody is Catalog # AAP31910 (Previous Catalog # AAPP02807)
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GTF2I
• Uniprot ID: Q75M86
• Protein Name: General transcription factor II-I
• Sample Type Confirmation:

  There is BioGPS gene expression data showing that GTF2I is expressed in HepG2

• Protein Accession #: NP_127493
• Purification: Affinity Purified
• Nucleotide Accession #: NM_033000
• Tested Species Reactivity: Human
• Gene Symbol: GTF2I
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
• Application: IHC, WB
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
• Image 1: Human HepG2
  
  WB Suggested Anti-GTF2I Antibody Titration: 0.2-1 ug/ml
  ELISA Titer: 1:312500
  Positive Control: HepG2 cell lysateThere is BioGPS gene expression data showing that GTF2I is expressed in HepG2
• Image 2: Human HepG2
  
  WB Suggested Anti-GTF2I AntibodyTitration: 2.5 ug/mlPositive Control: HepG2 Whole CellThere is BioGPS gene expression data showing that GTF2I is expressed in HepG2
• Image 3: Human Skin
  
  Rabbit Anti-GTF21 Antibody
  Catalog Number: ARP31910
  Paraffin Embedded Tissue: Human Skin
  Cellular Data: Squamous epithelial cells
  Antibody Concentration: 4.0-8.0 ug/ml
  Magnification: 400X
• Image 4: Human pancreas
  
  Rabbit Anti-GTF21 Antibody
  Catalog Number: ARP31910
  Paraffin Embedded Tissue: Human Pancreas
  Cellular Data: Epithelial cells of pancreatic acinus
  Antibody Concentration: 4.0-8.0 ug/ml
  Magnification: 400X