| Product Number |
ARP31905_T100 |
| Product Page |
www.avivasysbio.com/racgap1-antibody-n-terminal-region-arp31905-t100.html |
| Name |
RACGAP1 Antibody - N-terminal region (ARP31905_T100) |
| Protein Size (# AA) |
632 amino acids |
| Molecular Weight |
71kDa |
| NCBI Gene Id |
29127 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Rac GTPase activating protein 1 |
| Alias Symbols |
CYK4, ID-GAP, HsCYK-4, MgcRacGAP |
| Peptide Sequence |
Synthetic peptide located within the following region: EILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMKAETERSALD |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Niiya,F., et al., (2005) J. Biol. Chem. 280 (43), 36502-36509 |
| Description of Target |
Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC, and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases. |
| Protein Interactions |
MORF4L1; UBC; FZR1; MPG; TXNDC11; MPRIP; TANK; KIF23; AURKB; PPP2R4; ECT2; CDK1; IKBKG; CUL1; SH3KBP1; Racgap1; Shcbp1; Cd2ap; YWHAG; YWHAB; PRC1; SH3RF1; SLC26A8; SLC16A10; PRSS23; CHN2; MAP3K4; RND2; MAP3K10; TUBG1; TUBA4A; VAV1; NRAS; GRB2; SFN; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-RACGAP1 (ARP31905_T100) antibody |
| Blocking Peptide |
For anti-RACGAP1 (ARP31905_T100) antibody is Catalog # AAP31905 (Previous Catalog # AAPP02982) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human RACGAP1 |
| Uniprot ID |
Q9H0H5 |
| Protein Name |
Rac GTPase-activating protein 1 |
| Protein Accession # |
NP_037409 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_013277 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
RACGAP1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human HepG2
 | WB Suggested Anti-RACGAP1 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:1562500
Positive Control: HepG2 cell lysate |
|
