AATF Antibody - N-terminal region (ARP31867_P050)

Data Sheet
 
Product Number ARP31867_P050
Product Page www.avivasysbio.com/aatf-antibody-n-terminal-region-arp31867-p050.html
Name AATF Antibody - N-terminal region (ARP31867_P050)
Protein Size (# AA) 560 amino acids
Molecular Weight 63kDa
NCBI Gene Id 26574
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Apoptosis antagonizing transcription factor
Alias Symbols DED, BFR2, CHE1, CHE-1
Peptide Sequence Synthetic peptide located within the following region: EEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEE
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Burgdorf,S., et al., (2004) J. Biol. Chem. 279 (17), 17524-17534
Description of Target The AATF gene encodes a protein that was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.
Protein Interactions MDM2; DAPK3; AR; HIPK2; NGDN; UBC; TSG101; LIN28A; MMS19; ZNF468; NEDD4L; WHSC1; SMAD3; EFNB3; CPD; UBD; CAND1; PIN1; SIRT7; SUMO2; CHEK2; RELA; tat; MAGED1; PCBD2; SS18L1; LZTR1; MPHOSPH6; POLR2J; MPP6; PAWR; DAZAP2; ATR; ATM; CHEK1; LDOC1; SP1; RB1; MAP
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-AATF (ARP31867_P050) antibody
Blocking Peptide For anti-AATF (ARP31867_P050) antibody is Catalog # AAP31867 (Previous Catalog # AAPP02662)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human AATF
Uniprot ID Q9NY61
Protein Name Protein AATF
Protein Accession # NP_036270
Purification Affinity Purified
Nucleotide Accession # NM_012138
Tested Species Reactivity Human
Gene Symbol AATF
Predicted Species Reactivity Human, Mouse, Rat, Dog, Horse, Rabbit, Yeast
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Dog: 77%; Horse: 85%; Human: 100%; Mouse: 77%; Rabbit: 100%; Rat: 90%; Yeast: 90%
Image 1
Human Intestine
Human Intestine
Image 2
Human Liver
Human Liver
Image 3
Human kidney
WB Suggested Anti-AATF Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: Human kidney
 

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