Product Number |
ARP31867_P050 |
Product Page |
www.avivasysbio.com/aatf-antibody-n-terminal-region-arp31867-p050.html |
Name |
AATF Antibody - N-terminal region (ARP31867_P050) |
Protein Size (# AA) |
560 amino acids |
Molecular Weight |
63kDa |
NCBI Gene Id |
26574 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Apoptosis antagonizing transcription factor |
Alias Symbols |
DED, BFR2, CHE1, CHE-1 |
Peptide Sequence |
Synthetic peptide located within the following region: EEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEE |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Burgdorf,S., et al., (2004) J. Biol. Chem. 279 (17), 17524-17534 |
Description of Target |
The AATF gene encodes a protein that was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. |
Protein Interactions |
MDM2; DAPK3; AR; HIPK2; NGDN; UBC; TSG101; LIN28A; MMS19; ZNF468; NEDD4L; WHSC1; SMAD3; EFNB3; CPD; UBD; CAND1; PIN1; SIRT7; SUMO2; CHEK2; RELA; tat; MAGED1; PCBD2; SS18L1; LZTR1; MPHOSPH6; POLR2J; MPP6; PAWR; DAZAP2; ATR; ATM; CHEK1; LDOC1; SP1; RB1; MAP |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-AATF (ARP31867_P050) antibody |
Blocking Peptide |
For anti-AATF (ARP31867_P050) antibody is Catalog # AAP31867 (Previous Catalog # AAPP02662) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human AATF |
Uniprot ID |
Q9NY61 |
Protein Name |
Protein AATF |
Protein Accession # |
NP_036270 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_012138 |
Tested Species Reactivity |
Human |
Gene Symbol |
AATF |
Predicted Species Reactivity |
Human, Mouse, Rat, Dog, Horse, Rabbit, Yeast |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Dog: 77%; Horse: 85%; Human: 100%; Mouse: 77%; Rabbit: 100%; Rat: 90%; Yeast: 90% |
Image 1 | Human Intestine
| Human Intestine |
| Image 2 | Human Liver
| Human Liver |
| Image 3 | Human kidney
| WB Suggested Anti-AATF Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: Human kidney |
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