TLR6 Antibody - middle region (ARP31755_P050)

Data Sheet
 
Product Number ARP31755_P050
Product Page www.avivasysbio.com/tlr6-antibody-middle-region-arp31755-p050.html
Name TLR6 Antibody - middle region (ARP31755_P050)
Protein Size (# AA) 480 amino acids
Molecular Weight 53kDa
NCBI Gene Id 10333
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Toll-like receptor 6
Alias Symbols CD286
Peptide Sequence Synthetic peptide located within the following region: KCLVRVFQFLWPKPVEYLNIYNLTIIESIREEDFTYSKTTLKALTIEHIT
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Description of Target TLR6 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins.
Protein Interactions BTK; TRAP1; TLR2;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-TLR6 (ARP31755_P050) antibody
Blocking Peptide For anti-TLR6 (ARP31755_P050) antibody is Catalog # AAP31755 (Previous Catalog # AAPP23839)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human TLR6
Uniprot ID Q2NKL3
Protein Name TLR6 protein EMBL AAI11756.1
Protein Accession # AAI11756
Purification Affinity Purified
Nucleotide Accession # NM_006068
Tested Species Reactivity Human
Gene Symbol TLR6
Predicted Species Reactivity Human, Goat, Sheep
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Goat: 85%; Human: 100%; Sheep: 86%
Image 1
Human Jurkat
WB Suggested Anti-TLR6 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: Jurkat cell lysate
Image 2
Human kidney
Human kidney
 

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