| Product Number |
ARP31697_P050 |
| Product Page |
www.avivasysbio.com/fbxl11-antibody-n-terminal-region-arp31697-p050.html |
| Name |
FBXL11 Antibody - N-terminal region (ARP31697_P050) |
| Protein Size (# AA) |
782 amino acids |
| Molecular Weight |
86kDa |
| NCBI Gene Id |
22992 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Lysine (K)-specific demethylase 2A |
| Alias Symbols |
FBL7, CXXC8, FBL11, FBXL11, JHDM1A, LILINA |
| Peptide Sequence |
Synthetic peptide located within the following region: RIRYSQRLRGTMRRRYEDDGISDDEIEGKRTFDLEEKLHTNKYNANFVTF |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Strausberg,R.L., (2002) Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 |
| Description of Target |
FBXL11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box). The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXL11 belongs to the Fbls class and, in addition to an F-box, contains at least 6 highly degenerated leucine-rich repeats |
| Protein Interactions |
RB1; E2F1; EED; SKP1; MPG; ZNF512B; UBE2G2; SMAD7; SMAD3; HIST3H3; HIST2H3C; KIAA0368; ELAVL1; UBC; BCL6; FOS; RELA; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-KDM2A (ARP31697_P050) antibody |
| Blocking Peptide |
For anti-KDM2A (ARP31697_P050) antibody is Catalog # AAP31697 (Previous Catalog # AAPP02484) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human FBXL11 |
| Uniprot ID |
Q9Y2K7-3 |
| Protein Name |
Lysine-specific demethylase 2A |
| Protein Accession # |
AAH47486 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_001256405 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
KDM2A |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93% |
| Image 1 | Human HepG2
 | WB Suggested Anti-FBXL11 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysate |
|
| Image 2 | Human Muscle
 | HumanMuscle |
|
