| Product Number |
ARP31659_P050 |
| Product Page |
www.avivasysbio.com/evi1-antibody-c-terminal-region-arp31659-p050.html |
| Name |
EVI1 Antibody - C-terminal region (ARP31659_P050) |
| Protein Size (# AA) |
1051 amino acids |
| Molecular Weight |
118kDa |
| NCBI Gene Id |
2122 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
MDS1 and EVI1 complex locus |
| Alias Symbols |
EVI1, MDS1, KMT8E, PRDM3, RUSAT2, MDS1-EVI1, AML1-EVI-1 |
| Peptide Sequence |
Synthetic peptide located within the following region: HFTDSLKMRKMEDNQYSEAELSSFSTSHVPEELKQPLHRKSKSQAYAMML |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Chi,Y., et al., (2003) J. Biol. Chem. 278 (50), 49806-49811 |
| Description of Target |
EVI1 promotes cell proliferation by interacting with BRG1 and blocking the repression of BRG1 on E2F1 activity. |
| Protein Interactions |
PRMT1; PIAS4; SUMO1; SOX2; ELAVL1; SIRT1; KAT2B; SMAD4; SMAD3; SMAD2; SMAD1; EHMT2; SUV39H1; MECOM; HDAC1; HDAC4; CTBP2; CTBP1; CREBBP; MBD3; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-MECOM (ARP31659_P050) antibody |
| Blocking Peptide |
For anti-MECOM (ARP31659_P050) antibody is Catalog # AAP31659 (Previous Catalog # AAPP02446) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human EVI1 |
| Uniprot ID |
Q03112 |
| Protein Name |
MDS1 and EVI1 complex locus protein EVI1 |
| Protein Accession # |
NP_005232 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_005241 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
MECOM |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human 293T Whole Cell
 | Host: Rabbit
Target Name: MECOM
Sample Tissue: Human 293T Whole Cell
Antibody Dilution: 1ug/ml |
|
| Image 2 | Human Intestine
 | Human Intestine |
|
| Image 3 | 293T, HepG2
 | Host: Rabbit
Target: MECOM
Positive control (+): 293T (2T)
Negative control (-): HepG2 (HG)
Antibody concentration: 1ug/ml |
|
| Image 4 | Human 293T
 | Host: Rabbit
Target Name: EVI1
Sample Tissue: Human 293T
Antibody Dilution: 1.0ug/ml |
|
