| Product Number |
ARP31422_P050 |
| Product Page |
www.avivasysbio.com/spib-antibody-c-terminal-region-arp31422-p050.html |
| Name |
SPIB Antibody - C-terminal region (ARP31422_P050) |
| Protein Size (# AA) |
177 amino acids |
| Molecular Weight |
19kDa |
| NCBI Gene Id |
6689 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Spi-B transcription factor (Spi-1/PU.1 related) |
| Alias Symbols |
SPI-B |
| Peptide Sequence |
Synthetic peptide located within the following region: GQQKGNRKRMTYQKLARALRNYAKTGEIRKVKRKLTYQFDSALLPAVRRA |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Geng,C.D. (2005) J. Biol. Chem. 280 (52), 43264-43271 |
| Description of Target |
SPI1 (MIM 165170) and SPIB are members of a subfamily of ETS (see ETS1; MIM 164720) transcription factors. ETS proteins share a conserved ETS domain that mediates specific DNA binding. SPIB and SPI1 bind to a purine-rich sequence, the PU box (5-prime-GAGGAA-3-prime). |
| Protein Interactions |
TMEM37; SSB; GATA1; IRF4; MAPK3; MAPK8; CREBBP; TBP; CEBPB; RB1; SPI1; JUN; CSNK2A2; CSNK2A1; SPIB; E2F4; E2F3; E2F2; E2F1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-SPIB (ARP31422_P050) antibody |
| Blocking Peptide |
For anti-SPIB (ARP31422_P050) antibody is Catalog # AAP31422 (Previous Catalog # AAPP03080) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human SPIB |
| Uniprot ID |
Q01892 |
| Protein Name |
Transcription factor Spi-B |
| Sample Type Confirmation |
SPIB is supported by BioGPS gene expression data to be expressed in Daudi |
| Protein Accession # |
NP_003112 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_003121 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
SPIB |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
| Image 1 | Human spleen
 | WB Suggested Anti-SPIB Antibody Titration: 3 ug/ml
ELISA Titer: 1:62500
Positive Control: spleen tissue lysateSPIB is supported by RNA-seq data to be expressed in spleen |
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