Product Number |
ARP31421_P050 |
Product Page |
www.avivasysbio.com/spi1-antibody-middle-region-arp31421-p050.html |
Name |
SPI1 Antibody - middle region (ARP31421_P050) |
Protein Size (# AA) |
264 amino acids |
Molecular Weight |
30kDa |
NCBI Gene Id |
6688 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Spleen focus forming virus (SFFV) proviral integration oncogene spi1 |
Alias Symbols |
OF, PU.1, SFPI1, SPI-1, SPI-A |
Peptide Sequence |
Synthetic peptide located within the following region: HPSLGHQVSYLPRMCLQYPSLSPAQPSSDEEEGERQSPPLEVSDGEADGL |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Lin,M. et al., (2004) Cell. Microbiol. 6 (2), 175-186 |
Description of Target |
SPI1 is known to collaborate with multiple transcription factors and to regulate expression of immunoglobulin genes. Lack of SPI1 expression is associated with defective immunoglobulin transcription in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease |
Protein Interactions |
HOXA10; TMX1; VAV1; IRF1; IRF8; GATA3; GATA2; GATA1; GFI1; TBP; RB1; BYRF1; RARA; PML; HDAC3; SKI; SIN3A; HDAC1; BCL6; CEBPA; PIP; SPIB; SSRP1; IRF4; KAT6A; CEBPE; NFATC1; CREBBP; NONO; CEBPB; JUN; ERG; NFKB1; MITF; FUS; CREM; ATF1; CEBPD; MECP2; DNMT3B; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-SPI1 (ARP31421_P050) antibody |
Blocking Peptide |
For anti-SPI1 (ARP31421_P050) antibody is Catalog # AAP31421 (Previous Catalog # AAPP03079) |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human SPI1 |
Uniprot ID |
P17947 |
Protein Name |
Transcription factor PU.1 |
Protein Accession # |
NP_003111 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_003120 |
Tested Species Reactivity |
Human |
Gene Symbol |
SPI1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 100%; Rat: 100% |
Image 1 | Human Thymus
| WB Suggested Anti-SPI1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Human Thymus |
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