SPI1 Antibody - middle region (ARP31421_P050)

Data Sheet
 
Product Number ARP31421_P050
Product Page www.avivasysbio.com/spi1-antibody-middle-region-arp31421-p050.html
Name SPI1 Antibody - middle region (ARP31421_P050)
Protein Size (# AA) 264 amino acids
Molecular Weight 30kDa
NCBI Gene Id 6688
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Spleen focus forming virus (SFFV) proviral integration oncogene spi1
Alias Symbols OF, PU.1, SFPI1, SPI-1, SPI-A
Peptide Sequence Synthetic peptide located within the following region: HPSLGHQVSYLPRMCLQYPSLSPAQPSSDEEEGERQSPPLEVSDGEADGL
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Lin,M. et al., (2004) Cell. Microbiol. 6 (2), 175-186
Description of Target SPI1 is known to collaborate with multiple transcription factors and to regulate expression of immunoglobulin genes. Lack of SPI1 expression is associated with defective immunoglobulin transcription in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease
Protein Interactions HOXA10; TMX1; VAV1; IRF1; IRF8; GATA3; GATA2; GATA1; GFI1; TBP; RB1; BYRF1; RARA; PML; HDAC3; SKI; SIN3A; HDAC1; BCL6; CEBPA; PIP; SPIB; SSRP1; IRF4; KAT6A; CEBPE; NFATC1; CREBBP; NONO; CEBPB; JUN; ERG; NFKB1; MITF; FUS; CREM; ATF1; CEBPD; MECP2; DNMT3B;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-SPI1 (ARP31421_P050) antibody
Blocking Peptide For anti-SPI1 (ARP31421_P050) antibody is Catalog # AAP31421 (Previous Catalog # AAPP03079)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human SPI1
Uniprot ID P17947
Protein Name Transcription factor PU.1
Protein Accession # NP_003111
Purification Affinity Purified
Nucleotide Accession # NM_003120
Tested Species Reactivity Human
Gene Symbol SPI1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 100%; Rat: 100%
Image 1
Human Thymus
WB Suggested Anti-SPI1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human Thymus
 

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