| Product Number |
ARP31264_T100 |
| Product Page |
www.avivasysbio.com/creb1-antibody-n-terminal-region-arp31264-t100.html |
| Name |
CREB1 Antibody - N-terminal region (ARP31264_T100) |
| Protein Size (# AA) |
341 amino acids |
| Molecular Weight |
37kDa |
| NCBI Gene Id |
1385 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
CAMP responsive element binding protein 1 |
| Alias Symbols |
CREB, CREB-1 |
| Peptide Sequence |
Synthetic peptide located within the following region: QVHGVIQAAQPSVIQSPQVQTVQSSCKDLKRLFSGTQISTIAESEDSQES |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Melnikova,V.O., (2006) J. Biol. Chem. 281 (5), 2911-2922 |
| Description of Target |
CREB1 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway.This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. |
| Protein Interactions |
UBC; NCOR1; CREM; CREBBP; RPS6KA1; NR5A2; EP300; DEAF1; TP53; CREB1; PRKG1; YAP1; MAPK14; MEIS1; DAXX; TSSK4; AKT1; ATR; SIRT1; SRA1; DR1; ATF7; GSK3B; GSK3A; ATXN3; DNMT3B; RPS6KA5; YY1; RGS13; JUN; HDAC2; HDAC1; CCDC6; PPP1CA; SUMO1; TAF4; POU2F1; MYOD1 |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-CREB1 (ARP31264_T100) antibody |
| Blocking Peptide |
For anti-CREB1 (ARP31264_T100) antibody is Catalog # AAP31264 (Previous Catalog # AAPP24049) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human CREB1 |
| Uniprot ID |
P16220 |
| Protein Name |
Cyclic AMP-responsive element-binding protein 1 |
| Sample Type Confirmation |
CREB1 is supported by BioGPS gene expression data to be expressed in HepG2 |
| Protein Accession # |
NP_604391 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_134442 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
CREB1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Dog: 100%; Guinea Pig: 87%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human HepG2
 | WB Suggested Anti-CREB1 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysateCREB1 is supported by BioGPS gene expression data to be expressed in HepG2 |
|
| Image 2 | Human Testis
 | Rabbit Anti-CREB1 Antibody
Catalog Number: ARP31264_T100
Formalin Fixed Paraffin Embedded Tissue: Human Testis Tissue
Observed Staining: Nucleus
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec |
|
