| Product Number |
ARP30317_P050 |
| Product Page |
www.avivasysbio.com/stat3-antibody-middle-region-arp30317-p050.html |
| Name |
STAT3 Antibody - middle region (ARP30317_P050) |
| Protein Size (# AA) |
770 amino acids |
| Molecular Weight |
88kDa |
| NCBI Gene Id |
6774 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Signal transducer and activator of transcription 3 (acute-phase response factor) |
| Alias Symbols |
APRF, HIES, ADMIO, ADMIO1 |
| Peptide Sequence |
Synthetic peptide located within the following region: SNTIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATS |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Ohbayashi,N., (2008) Biochem. Biophys. Res. Commun. 371 (4), 823-828 |
| Description of Target |
STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act a |
| Protein Interactions |
MTOR; GADD45A; BMX; BLK; UBC; SYK; LMO2; SRI; HIC1; GNB2; USP22; RELA; COPS5; BRD4; ADRB2; PSMG3; TBCD; TBC1D15; PUS7; LUC7L2; ARFIP1; IVNS1ABP; MSH2; BMH1; SIN3A; EGFR; PIAS3; HDAC3; SRC; LYN; JAK3; JAK2; HES5; TRIM28; HES1; HCK; FYN; FGR; HNRNPM; SULT2A |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-STAT3 (ARP30317_P050) antibody |
| Blocking Peptide |
For anti-STAT3 (ARP30317_P050) antibody is Catalog # AAP30317 (Previous Catalog # AAPS08804) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human STAT3 |
| Uniprot ID |
P40763 |
| Protein Name |
Signal transducer and activator of transcription 3 |
| Protein Accession # |
NP_644805 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_139276 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
STAT3 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish |
| Application |
WB, IHC |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 91% |
| Image 1 | Human THP-1
 | WB Suggested Anti-STAT3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: THP-1 cell lysate |
|
| Image 2 | Human Lung
 | Rabbit Anti-STAT3 Antibody
Catalog Number: ARP30317_P050
Formalin Fixed Paraffin Embedded Tissue: Human Lung Tissue
Observed Staining: Cytoplasm
Primary Antibody Concentration: 1:600
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec |
|
