PDPK1 Antibody - middle region (ARP30313_P050)

Data Sheet
 
Product Number ARP30313_P050
Product Page www.avivasysbio.com/pdpk1-antibody-middle-region-arp30313-p050.html
Name PDPK1 Antibody - middle region (ARP30313_P050)
Protein Size (# AA) 556 amino acids
Molecular Weight 63kDa
NCBI Gene Id 5170
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name 3-phosphoinositide dependent protein kinase-1
Alias Symbols PDK1, PDPK2, PDPK2P, PRO0461
Peptide Sequence Synthetic peptide located within the following region: IIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVS
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Lin,H.J., (2005) Br. J. Cancer 93 (12), 1372-1381
Description of Target PDPK1 phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. It may play a general role in signaling processes and in development.
Protein Interactions SRPK1; AKT1; APP; YWHAQ; STRAP; SGK1; UBC; SOCS3; PEA15; TCAP; ZNF133; SMARCB1; SBF1; XRCC6; BLMH; FAM213B; CARD11; C2orf44; KATNBL1; PNO1; DDIT4; PHAX; LUC7L2; ZC3HC1; GIT1; POLDIP2; XPO7; PRKCQ; G3BP1; PA2G4; SND1; TBL2; RPS6KB2; RPS6KB1; CDAN1; AKTIP;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-PDPK1 (ARP30313_P050) antibody
Blocking Peptide For anti-PDPK1 (ARP30313_P050) antibody is Catalog # AAP30313 (Previous Catalog # AAPS08803)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human PDPK1
Uniprot ID O15530
Protein Name 3-phosphoinositide-dependent protein kinase 1
Protein Accession # NP_002604
Purification Affinity Purified
Nucleotide Accession # NM_002613
Tested Species Reactivity Human
Gene Symbol PDPK1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Image 1
Human Jurkat
WB Suggested Anti-PDPK1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysate
 

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