| Product Number |
ARP30107_T100 |
| Product Page |
www.avivasysbio.com/tsc22d4-antibody-n-terminal-region-arp30107-t100.html |
| Name |
TSC22D4 Antibody - N-terminal region (ARP30107_T100) |
| Protein Size (# AA) |
395 amino acids |
| Molecular Weight |
41kDa |
| NCBI Gene Id |
81628 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
TSC22 domain family, member 4 |
| Description |
|
| Alias Symbols |
THG1, THG-1, TILZ2 |
| Peptide Sequence |
Synthetic peptide located within the following region: SGGKKKSSFQITSVTTDYEGPGSPGASDPPTPQPPTGPPPRLPNGEPSPD |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Scherer,S.W., et al., (2003) Science 300 (5620), 767-772 |
| Description of Target |
TSC22D4 is a leucine zipper-containing protein that is highly conserved during evolution. It is transcriptionally up-regulated by many different stimuli, including anti-cancer drugs and growth inhibitors. TSC22D4 may play a suppressive role in tumorigenesis. |
| Protein Interactions |
NRBP2; KRT40; CCDC146; TEX11; PIH1D1; ZMYND10; APIP; NRBP1; MYLIP; ZBTB24; POLR1C; BLZF1; PRKAA2; PRKAA1; PPL; PIN1; MAD2L1; LMO2; GOLGA2; AES; BZRAP1; KEAP1; SMAD3; LBP; KPNA2; CLU; SACS; AIFM1; PRNP; PCBP1; ZNF580; SYT17; LNX1; NOC4L; ENKD1; FRMD6; LRP2 |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-TSC22D4 (ARP30107_T100) antibody |
| Blocking Peptide |
For anti-TSC22D4 (ARP30107_T100) antibody is Catalog # AAP30107 (Previous Catalog # AAPH00283) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human TSC22D4 |
| Uniprot ID |
Q9Y3Q8 |
| Protein Name |
TSC22 domain family protein 4 |
| Publications |
Canterini, S. et al. Subcellular TSC22D4 localization in cerebellum granule neurons of the mouse depends on development and differentiation. Cerebellum 11, 28-40 (2012). 20878296
Canterini, S., Bosco, A., De Matteis, V., Mangia, F. & Fiorenza, M. T. THG-1pit moves to nucleus at the onset of cerebellar granule neurons apoptosis. Mol. Cell. Neurosci. 40, 249-57 (2009). 19084601
NRBP1-Containing CRL2/CRL4A Regulates Amyloid β Production by Targeting BRI2 and BRI3 for Degradation. Cell Rep. 30, 3478-3491.e6 (2020). 32160551 |
| Protein Accession # |
NP_112197 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_030935 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
TSC22D4 |
| Predicted Species Reactivity |
Human, Rat, Dog, Guinea Pig |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Dog: 90%; Guinea Pig: 93%; Human: 100%; Rat: 77% |
| Image 1 | Human HepG2
 | WB Suggested Anti-TSC22D4 Antibody Titration: 0.5ug/ml
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysate |
|
| Image 2 | Human Lung
 | Rabbit Anti-TSC22D4 Antibody
Catalog Number: ARP30107
Paraffin Embedded Tissue: Human Lung
Cellular Data: Alveolar cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 3 | Human kidney
 | Rabbit Anti-TSC22D4 Antibody
Catalog Number: ARP30107
Paraffin Embedded Tissue: Human Kidney
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
