| Product Number |
ARP30002_P050 |
| Product Page |
www.avivasysbio.com/cbx4-antibody-n-terminal-region-arp30002-p050.html |
| Name |
CBX4 Antibody - N-terminal region (ARP30002_P050) |
| Protein Size (# AA) |
560 amino acids |
| Molecular Weight |
61kDa |
| NCBI Gene Id |
8535 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Chromobox homolog 4 |
| Alias Symbols |
PC2, NBP16 |
| Peptide Sequence |
Synthetic peptide located within the following region: LLIAFQNRERQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQDSSTD |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Kagey,M.H., et al., (2003) Cell 113 (1), 127-137 |
| Description of Target |
The polycomb group (PcG) protein HPC2, which functions as a transcriptional suppressor, is a candidate of KyoT2-binding proteins. Pc2 dramatically enhances CtBP sumoylation. Pc2 is a SUMO E3, and Polycomb Group bodies may be sumoylation centers. |
| Protein Interactions |
Rnf111; SUMO1; NEDD8; CBS; BMI1; EED; RNF2; HECW2; SOX2; YWHAE; YWHAB; CCDC158; DIS3L2; HIST4H4; CBX2; PARP12; RNF213; ZKSCAN7; DCAF6; KDM3A; MYCBP2; ANKRD26; PSME3; TRANK1; CBX4; HIST1H2AB; YWHAZ; SKIL; NPM1; HIST1H2BB; GTF2I; PHC2; CSNK2B; CSNK2A2; CSNK |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-CBX4 (ARP30002_P050) antibody |
| Blocking Peptide |
For anti-CBX4 (ARP30002_P050) antibody is Catalog # AAP30002 (Previous Catalog # AAPH00102) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human CBX4 |
| Uniprot ID |
O00257-2 |
| Protein Name |
E3 SUMO-protein ligase CBX4 |
| Publications |
Hao, L., Midic, U., Garriga, J. & Latham, K. E. Contribution of CBX4 to cumulus oophorus cell phenotype in mice and attendant effects in cumulus cell cloned embryos. Physiol. Genomics 46, 66-80 (2014). 24280258 |
| Sample Type Confirmation |
CBX4 is supported by BioGPS gene expression data to be expressed in Jurkat |
| Protein Accession # |
NP_003646 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_003655 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
CBX4 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 77% |
| Image 1 | Human kidney
 | Rabbit Anti-CBX 4 Antibody
Catalog Number: ARP30002
Paraffin Embedded Tissue: Human Kidney
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 2 | Human Jurkat
 | WB Suggested Anti-CBX4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysateCBX4 is supported by BioGPS gene expression data to be expressed in Jurkat |
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