| Sku |
AAP58473 |
| Old sku |
AAPP34569 |
| Price |
$99.00 |
| Name |
GPX4 Peptide - middle region (AAP58473) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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|
| Size |
100 ug |
| Gene |
GPX4 |
| Alias symbols |
MCSP, PHGPx, snGPx, snPHGPx |
| Gene id |
2879 |
| Description of target |
Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. |
| Swissprot id |
P36969 |
| Protein accession num |
NP_002076 |
| Nucleotide accession num |
NM_002085 |
| Protein size |
197 amino acids |
| Molecular weight |
22kDa |
| Application |
IHC, WB |
| Partner proteins |
OTUD5 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Peters,U., (2008) Cancer Epidemiol. Biomarkers Prev. 17 (5), 1144-1154 |
| Description |
This is a synthetic peptide designed for use in combination with anti-GPX4 antibody (Catalog #: ARP58473_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
