Sku |
AAP57917 |
Old sku |
AAPP32328 |
Price |
$99.00 |
Name |
TCF7L1 Peptide - N-terminal region (AAP57917) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
TCF7L1 |
Alias symbols |
TCF-3, TCF3 |
Gene id |
83439 |
Description of target |
TCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance. |
Swissprot id |
Q9HCS4 |
Protein accession num |
NP_112573 |
Nucleotide accession num |
NM_031283 |
Protein size |
588 amino acids |
Molecular weight |
63kDa |
Application |
WB |
Partner proteins |
CTNNB1,CTNNB1 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Hillier,L.W., (2005) Nature 434 (7034), 724-731 |
Description |
This is a synthetic peptide designed for use in combination with anti-TCF7L1 antibody (Catalog #: ARP57917_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |