TCF7L1 Peptide - N-terminal region (AAP57917)

Data Sheet
 
Sku AAP57917
Old sku AAPP32328
Price $99.00
Name TCF7L1 Peptide - N-terminal region (AAP57917)
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Size 100 ug
Gene TCF7L1
Alias symbols TCF-3, TCF3
Gene id 83439
Description of target TCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance.
Swissprot id Q9HCS4
Protein accession num NP_112573
Nucleotide accession num NM_031283
Protein size 588 amino acids
Molecular weight 63kDa
Application WB
Partner proteins CTNNB1,CTNNB1
Quality control The peptide is characterized by mass spectroscopy
Key reference Hillier,L.W., (2005) Nature 434 (7034), 724-731
Description This is a synthetic peptide designed for use in combination with anti-TCF7L1 antibody (Catalog #: ARP57917_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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