TRAPPC2 Peptide - middle region (AAP50568)

Data Sheet
 
Sku AAP50568
Old sku AAPP13941
Price $99.00
Name TRAPPC2 Peptide - middle region (AAP50568)
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Size 100 ug
Gene TRAPPC2
Alias symbols MIP-2A, SEDL, SEDT, TRS20, ZNF547L, hYP38334, MIP2A, TRAPPC2P1
Gene id 6399
Description of target TRAPPC2 prevents MBP1-mediated transcriptional repression and antagonizes MBP1-mediated cell death. TRAPPC2 may play a role in vesicular transport from endoplasmic reticulum to Golgi.The protein encoded by this gene is thought to be part of a large multisubunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind MBP1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseuodogenes are found on chromosomes 8 and Y. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been found for this gene.
Swissprot id O14582
Protein accession num NP_055378
Nucleotide accession num NM_014563
Protein size 140 amino acids
Molecular weight 16kDa
Application WB
Partner proteins CLIC1,CLIC2,CLIC1,CLIC2,ENO1,JOSD2
Subunit 2
Quality control The peptide is characterized by mass spectroscopy
Key reference Ross,M.T., (2005) Nature 434 (7031), 325-337
Description This is a synthetic peptide designed for use in combination with anti-TRAPPC2 antibody (Catalog #: ARP50568_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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