| Sku |
AAP48668 |
| Old sku |
AAPP28718 |
| Name |
PCMT1 (protein-L-isoaspartate (D-aspartate) O-methyltransferase) Blocking Peptide (100ug) |
| Purchase info |
To purchase this peptide:
- Copy peptide #
- Click on this link
- Paste into field "Peptide Number"
|
| Size |
100 ug |
| Gene symbol |
PCMT1 |
| Nucleotide accession num |
NM_005389 |
| Protein accession num |
NP_005380 |
| Swissprot id |
P22061 |
| Protein size |
227 amino acids |
| Molecular weight |
25kDa |
| Product format |
Lyophilized powder |
| Gene id |
5110 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Price |
$99.00 |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Availability |
In Stock |
| Partner proteins |
APOA1,CHD3,CREBBP,CHD3,EIF1B,VHL |
| Key reference |
Kosugi,S., (2008) Biochem. Biophys. Res. Commun. 371 (1), 22-27 |
| Description |
This is a synthetic peptide designed for use in combination with anti-PCMT1 antibody (Catalogue #: ARP48668_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Description of target |
Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Protocol |
|
| Tips |
See our General FAQ page. |
