DKK1 Peptide (AAP48015)

Data Sheet
 
Sku AAP48015
Old sku AAPS20606
Price $99.00
Name DKK1 Peptide (AAP48015)
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Size 100 ug
Gene DKK1
Alias symbols DKK-1, SK
Gene id 22943
Description of target DKK1 is a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
Swissprot id O94907
Protein accession num NP_036374
Nucleotide accession num NM_012242
Protein size 266 amino acids
Molecular weight 26kDa
Application WB
Partner proteins CTNNB1,KREMEN1,LRP5,LRP6,MDFI,SMAD9,CORO1A,LRP6,MDFI
Quality control The peptide is characterized by mass spectroscopy
Key reference Ai,M., (2005) Mol. Cell. Biol. 25 (12), 4946-4955
Description This is a synthetic peptide designed for use in combination with anti-DKK1 antibody (Catalog #: ARP48015_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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