Sku |
AAP48015 |
Old sku |
AAPS20606 |
Price |
$99.00 |
Name |
DKK1 Peptide (AAP48015) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
DKK1 |
Alias symbols |
DKK-1, SK |
Gene id |
22943 |
Description of target |
DKK1 is a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. |
Swissprot id |
O94907 |
Protein accession num |
NP_036374 |
Nucleotide accession num |
NM_012242 |
Protein size |
266 amino acids |
Molecular weight |
26kDa |
Application |
WB |
Partner proteins |
CTNNB1,KREMEN1,LRP5,LRP6,MDFI,SMAD9,CORO1A,LRP6,MDFI |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Ai,M., (2005) Mol. Cell. Biol. 25 (12), 4946-4955 |
Description |
This is a synthetic peptide designed for use in combination with anti-DKK1 antibody (Catalog #: ARP48015_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |