Sku |
AAP46104 |
Old sku |
AAPP26966 |
Price |
$99.00 |
Name |
CAD Peptide (AAP46104) |
Purchase info |
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|
Size |
100 ug |
Gene |
CAD |
Gene id |
790 |
Description of target |
CAD is a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Swissprot id |
P27708 |
Protein accession num |
NP_004332 |
Nucleotide accession num |
NM_004341 |
Protein size |
2225 amino acids |
Molecular weight |
243kDa |
Application |
WB |
Partner proteins |
CAD,CASP3,MAPK1,PPP1CA,PPP2CA,PRKACA,YWHAG |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Olsen,J.V., (2006) Cell 127 (3), 635-648 |
Description |
This is a synthetic peptide designed for use in combination with anti-CAD antibody (Catalog #: ARP46104_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |