SLC27A2 Peptide - N-terminal region (AAP43855)

Data Sheet
 
Sku AAP43855
Old sku AAPS14404
Price $99.00
Name SLC27A2 Peptide - N-terminal region (AAP43855)
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Size 100 ug
Gene SLC27A2
Alias symbols ACSVL1, FACVL1, FATP2, HsT17226, VLACS, VLCS, hFACVL1
Gene id 11001
Description of target SLC27A2 is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy.The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy.
Swissprot id O14975
Protein accession num NP_003636
Nucleotide accession num NM_003645
Protein size 620 amino acids
Molecular weight 70kDa
Application IHC, WB
Quality control The peptide is characterized by mass spectroscopy
Key reference Mihalik,S.J., (2002) J. Biol. Chem. 277 (27), 24771-24779
Description This is a synthetic peptide designed for use in combination with anti-SLC27A2 antibody (Catalog #: ARP43855_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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