| Sku |
AAP41392 |
| Old sku |
AAPP24130 |
| Price |
$99.00 |
| Name |
TPM1 Peptide (AAP41392) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
TPM1 |
| Alias symbols |
CMH3, TMSA, TPM1-alpha, CMD1Y, C15orf13, HTM-alpha |
| Gene id |
7168 |
| Description of target |
TPM1 is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction.This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. |
| Swissprot id |
P09493 |
| Protein accession num |
NP_000357 |
| Nucleotide accession num |
NM_000366 |
| Protein size |
284 amino acids |
| Molecular weight |
31kDa |
| Application |
IHC, WB |
| Partner proteins |
ACTB,C19orf50,EPB41,JUN,PKD2,S100A2,TMOD2,TNNT1,TNNT2,TPM2,C19orf50,CNN1,TNNT1,TNNT2,TPM1,TPM2 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Lin,J.C. (2005) Mol. Cell. Biol. 25 (22), 10111-10121 |
| Description |
This is a synthetic peptide designed for use in combination with anti-TPM1 antibody (Catalog #: ARP41392_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
