HNRPL Peptide - N-terminal region (AAP40367)

Data Sheet
 
Sku AAP40367
Old sku AAPP23492
Price $99.00
Name HNRPL Peptide - N-terminal region (AAP40367)
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Size 100 ug
Gene HNRNPL
Alias symbols P/OKcl.14, hnRNP-L, HNRPL
Gene id 3191
Description of target Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene. Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.
Swissprot id P14866
Protein accession num NP_001524
Nucleotide accession num NM_001533
Protein size 589 amino acids
Molecular weight 65kDa
Application IHC, WB
Partner proteins TP53; FUS; TRIM68; SUMO2; SUMO3; IVNS1ABP; UBC; MDM2; RPA3; RPA2; RPA1; ILF3; HNRNPA2B1; EED; VHL; VEGFA; RNF2; NEDD4; ITCH; FBXO6; HMGA1; vif; TP63; UBL4A; WHSC1; VCAM1; ITGA4; IL7R; IFIT3; IFIT2; FN1; DAB2; CSNK2A1; EIF4A3; MAGOH; HNRNPA3; NPLOC4; LSM14
Quality control The peptide is characterized by mass spectroscopy
Key reference Guang,S., (2005) Mol. Cell. Biol. 25 (15), 6303-6313
Description This is a synthetic peptide designed for use in combination with anti-HNRPL antibody (Catalog #: ARP40367_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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