| Sku |
AAP39715 |
| Old sku |
AAPP21740 |
| Price |
$99.00 |
| Name |
ZNF496 Peptide (AAP39715) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
ZNF496 |
| Alias symbols |
NIZP1, ZFP496, ZKSCAN17 |
| Gene id |
84838 |
| Description of target |
ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn(II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif. |
| Swissprot id |
Q96IT1 |
| Protein accession num |
NP_116141 |
| Nucleotide accession num |
NM_032752 |
| Protein size |
587 amino acids |
| Molecular weight |
67kDa |
| Application |
WB |
| Partner proteins |
ARR3,NSD1,ZNF446,ARR3,NSD1,ZNF446 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Rual,J.F., (2005) Nature 437 (7062), 1173-1178 |
| Description |
This is a synthetic peptide designed for use in combination with anti-ZNF496 antibody (Catalog #: ARP39715_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
