FOXA2 Peptide (AAP39508)

Data Sheet
 
Sku AAP39508
Old sku AAPP21524
Price $99.00
Name FOXA2 Peptide (AAP39508)
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Size 100 ug
Gene FOXA2
Alias symbols HNF3B, TCF3B
Gene id 3170
Description of target FOXA2 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young.This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene.
Swissprot id Q9Y261
Protein accession num NP_710141
Nucleotide accession num NM_153675
Protein size 457 amino acids
Molecular weight 50kDa
Application WB
Partner proteins EN2,GSC,HOXA5,MIP,NCOA1,ONECUT1,OTX2,TLE1,EN2,GSC,HOXA5,LHX1,NCOA1,ONECUT1,OTX2,TLE1
Quality control The peptide is characterized by mass spectroscopy
Key reference Verschuur,M., (2005) J. Biol. Chem. 280 (17), 16763-16771
Description This is a synthetic peptide designed for use in combination with anti-FOXA2 antibody (Catalog #: ARP39508_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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