| Sku |
AAP39381 |
| Old sku |
AAPP21392 |
| Name |
DMAP1 (DNA methyltransferase 1 associated protein 1) Blocking Peptide (100ug) |
| Purchase info |
To purchase this peptide:
- Copy peptide #
- Click on this link
- Paste into field "Peptide Number"
|
| Size |
100 ug |
| Gene symbol |
DMAP1 |
| Nucleotide accession num |
NM_019100 |
| Protein accession num |
NP_061973 |
| Swissprot id |
Q9NPF5 |
| Protein size |
467 amino acids |
| Molecular weight |
53kDa |
| Product format |
Lyophilized powder |
| Gene id |
55929 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Price |
$99.00 |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Availability |
In Stock |
| Partner proteins |
DNMT1,RGS6,C19orf2,C20orf20,DAXX,DNMT1,HDAC2,ING1,RGS6,TOMM34,TSG101,C19orf2,DNMT1,ING1,ING3,RGS6,RUVBL1,RUVBL2,TSG101 |
| Key reference |
Oh,J.H., et al., (2005) Mamm. Genome 16 (12), 942-954 |
| Description |
This is a synthetic peptide designed for use in combination with anti-DMAP1 antibody (Catalogue #: ARP39381_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Description of target |
DMAP1 is a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described. |
| Protocol |
|
| Tips |
See our General FAQ page. |
|
|
